Evidence map›Paper›PMID 34185230›Full record

ArticleSleep & breathing = Schlaf & Atmung2022

Can the complete blood count be used as a reliable screening tool for obstructive sleep apnea?

Emer Cummins, Rida Waseem, Deween Piyasena, Chew Yin Wang, Colin Suen, Clodagh Ryan, Jean Wong, Meir Kryger, Frances Chung

Abstract read
PubMed Publisher
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

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  11. Serendipity.Sleep advances : a journal of the Sleep Research Society · 2023
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Emer CumminsDepartment of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, ON, Canada.
Rida WaseemDepartment of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, ON, Canada.
Deween PiyasenaDepartment of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, ON, Canada.
Chew Yin WangUniversity of Malaya, Kuala Lumpur, Malaysia.
Colin SuenDepartment of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, ON, Canada.ORCID 0000-0001-8274-991X
Clodagh RyanCentre of Sleep Health and Research, Department of Medicine, University Health Network, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-2372-965X
Jean WongDepartment of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-7213-4898
Meir KrygerYale School of Medicine, New Haven, CT, USA.
Frances ChungDepartment of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, ON, Canada. frances.chung@uhn.ca.ORCID 0000-0001-9576-3606
University Health Network · CAUniversity of Malaya · MYYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSince hypoxia increases erythropoietin production and inflammation, the complete blood count (CBC) has been proposed as an inexpensive alternative for obstructive sleep apnea (OSA) screening. The objective of this study was to determine whether or not intermittent hypoxia and OSA severity, as measured by the mean oxygen saturation (SpO

methodsThis retrospective study included a total of 941 surgical patients who had a pre-operative home sleep study. The pre-operative CBC was extracted from the electronic patient records. Patients were stratified according to their AHI scores, into mild (AHI ≥ 5 - < 15), moderate (AHI ≥ 15 - < 30), and severe (AHI ≥ 30) OSA groups.

resultsThere were 244 patients without OSA, 294 with mild, 223 with moderate, and 180 with severe OSA. Our analysis showed that hemoglobin (P = 0.010), hematocrit (P = 0.027), and basophils (P = 0.006) showed significant changes among the different severities of OSA. For mean SpO

conclusionHemoglobin, MCV, and basophils were independently associated with intermittent hypoxia defined by mean SpO

Indexed as

Sleep Apnea, ObstructiveBlood Cell CountHumansHypoxiaPolysomnographyRetrospective StudiesApnea–hypopnea indexComplete blood countHematological parametersHemoglobinHypoxiaObstructive sleep apnea

Identifiers

PMID34185230
OpenAlexW3173439477

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.