Evidence map›Paper›PMID 34185216›Full record

ArticleWiener medizinische Wochenschrift (1946)2022

qSOFA score poorly predicts critical progression in COVID-19 patients.

Sven Heldt, Matthias Neuböck, Nora Kainzbauer, Guangyu Shao, Thomas Tschoellitsch, Martin Duenser, Bernhard Kaiser, Markus Winkler, Christian Paar, Jens Meier and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Wiener medizinische Wochenschrift (1946), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Sven HeldtDepartment of Pulmonary Medicine, Kepler University Hospital, Krankenhausstraße 9, 4021, Linz, Austria.
Matthias NeuböckDepartment of Pulmonary Medicine, Kepler University Hospital, Krankenhausstraße 9, 4021, Linz, Austria.
Nora KainzbauerDepartment of Pulmonary Medicine, Kepler University Hospital, Krankenhausstraße 9, 4021, Linz, Austria.
Guangyu ShaoDepartment of Pulmonary Medicine, Kepler University Hospital, Krankenhausstraße 9, 4021, Linz, Austria.
Thomas TschoellitschDepartment of Anesthesiology and Intensive Care Medicine, Kepler University Hospital, Linz, Austria.
Martin DuenserDepartment of Anesthesiology and Intensive Care Medicine, Kepler University Hospital, Linz, Austria.
Bernhard KaiserDepartment of Pulmonary Medicine, Kepler University Hospital, Krankenhausstraße 9, 4021, Linz, Austria.
Markus WinklerDepartment of Pathology and Microbiology, Kepler University Hospital, Linz, Austria.
Christian PaarInstitute of Laboratory Medicine, Kepler University Hospital, Linz, Austria.
Jens MeierDepartment of Anesthesiology and Intensive Care Medicine, Kepler University Hospital, Linz, Austria.
Bernd LamprechtDepartment of Pulmonary Medicine, Kepler University Hospital, Krankenhausstraße 9, 4021, Linz, Austria.
Helmut J F SalzerDepartment of Pulmonary Medicine, Kepler University Hospital, Krankenhausstraße 9, 4021, Linz, Austria. helmut.salzer@kepleruniklinikum.at.
Kepler Universitätsklinikum · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn December 2019, the new virus infection coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged. Simple clinical risk scores may improve the management of COVID-19 patients. Therefore, the aim of this pilot study was to evaluate the quick Sequential Organ Failure Assessment (qSOFA) score, which is well established for other diseases, as an early risk assessment tool predicting a severe course of COVID-19.

methodsWe retrospectively analyzed data from adult COVID-19 patients hospitalized between March and July 2020. A critical disease progress was defined as admission to intensive care unit (ICU) or death.

resultsOf 64 COVID-19 patients, 33% (21/64) had a critical disease progression from which 13 patients had to be transferred to ICU. The COVID-19-associated mortality rate was 20%, increasing to 39% after ICU admission. All patients without a critical progress had a qSOFA score ≤ 1 at admission. Patients with a critical progress had in only 14% (3/21) and in 20% (3/15) of cases a qSOFA score ≥ 2 at admission (p = 0.023) or when measured directly before critical progression, respectively, while 95% (20/21) of patients with critical progress had an impairment oxygen saturation (SO

conclusionA low qSOFA score cannot be used to assume short-term stable or noncritical disease status in COVID-19.

Indexed as

COVID-19SepsisAdultHospital MortalityHumansIntensive Care UnitsOrgan Dysfunction ScoresPilot ProjectsPrognosisRetrospective StudiesSARS-CoV-2AustriaDeathIntensive care unitOrgan dysfunction scoresSARS-CoV-2

Identifiers

PMID34185216
PMCPMC8239483
OpenAlexW3177087820

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.