Evidence map›Paper›PMID 34185192›Full record

ArticleJournal of medical ultrasonics (2001)2021

Elucidation of spleen elasticity and viscosity in a carbon tetrachloride rat model of liver cirrhosis using a new ultrasound elastography.

Yoshihiro Furuichi, Katsutoshi Sugimoto, Hisashi Oshiro, Masakazu Abe, Hirohito Takeuchi, Yuu Yoshimasu, Takao Itoi

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Article in Journal of medical ultrasonics (2001), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Yoshihiro FuruichiDepartment of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan. furuichi@tokyo-med.ac.jp.ORCID http://orcid.org/0000-0002-8986-9823
Katsutoshi SugimotoDepartment of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.
Hisashi OshiroDepartment of Pathology, Jichi Medical University, Tochigi, Japan.
Masakazu AbeDepartment of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.
Hirohito TakeuchiDepartment of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.
Yuu YoshimasuDepartment of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.
Takao ItoiDepartment of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.

Funding

Ministry of Health, Labour and Welfare 17K09441
6 · The paper itself

Abstract

purposeMeasurement of spleen stiffness (SS) using ultrasound (US) elastography is useful for predicting portal hypertension. However, the mechanism leading to increased SS remains unclear. We jointly developed a new US elastography system (Aplio i-series, Canon Medical Systems) that can easily measure organ viscosity (dispersion slope: DS). We analyzed the cause of increased SS by calculating the shear wave speed (SWs, which reflects fibrosis) and DS of the spleen in carbon tetrachloride (CCL

methodsA total of 13 Sprague-Dawley rats were randomly divided into four groups (C group: 3 rats as control, 2D group: 3 rats injected with CCL

resultsThe spleen SWs of the 6W group was significantly higher than that of the C group (p = 0.044). The spleen DS did not change after CCL

conclusionSS increased due to fibrosis and can be predicted based on SWs and DS values.

Indexed as

Elasticity Imaging TechniquesAnimalsCarbon TetrachlorideElasticityLiverLiver CirrhosisRatsRats, Sprague-DawleySpleenViscosityCarbon TetrachlorideDispersion slopeElastographyShear wavesSpleen stiffnessViscosity

Identifiers

PMID34185192

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.