Evidence map›Paper›PMID 34184895›Full record

ArticleThe journal of physical chemistry letters2021

Conformational Dynamics of Histone H3 Tails in Chromatin.

Mohamad Zandian, Nicole Gonzalez Salguero, Matthew D Shannon, Rudra N Purusottam, Theint Theint, Michael G Poirier, Christopher P Jaroniec

Open access · greenAbstract read
In one paragraph

Article in The journal of physical chemistry letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Beyond the mono-nucleosome.Biochemical Society transactions · 2025
    Review
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  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Correlating histone acetylation with nucleosome core particle dynamics and function.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  13. Arginine anchor points govern H3 tail dynamics.Frontiers in molecular biosciences · 2023
    Article
  14. Article
  15. Probing Watson-Crick and Hoogsteen base pairing in duplex DNA using dynamic nuclear polarization solid-state NMR spectroscopy.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  16. Review
  17. Article
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mohamad ZandianDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio 43210, United States.
Nicole Gonzalez SalgueroDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio 43210, United States.
Matthew D ShannonDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio 43210, United States.
Rudra N PurusottamDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio 43210, United States.
Theint TheintDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio 43210, United States.
Michael G PoirierDepartment of Physics, The Ohio State University, Columbus, Ohio 43210, United States.
Christopher P JaroniecDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio 43210, United States.ORCID https://orcid.org/0000-0003-0364-2888
The Ohio State University · US

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Tasleem J Padamsee · 1985 to 2026
$132.3M
800 MHz Solid-State NMR Spectrometer for Biomacromolecular Structure and DynamicsS10OD012303 · OD · OHIO STATE UNIVERSITY · PI JARONIEC, CHRISTOPHER P · 2012 to 2012
$2.0M
Structural and dynamic studies of histone tails in chromatin by magnetic resonance spectroscopyR01GM123743 · NIGMS · OHIO STATE UNIVERSITY · PI JARONIEC, CHRISTOPHER P, POIRIER, MICHAEL GUY · 2017 to 2018
$658k
Structural and dynamic studies of histone tails in chromatin by magnetic resonance spectroscopyR01GM118664 · NIGMS · OHIO STATE UNIVERSITY · PI JARONIEC, CHRISTOPHER P · 2016 to 2017
$622k
NCI NIH HHS P30 CA016058NIGMS NIH HHS R01 GM118664NIGMS NIH HHS R01 GM123743NIH HHS S10 OD012303
6 · The paper itself

Abstract

Chromatin is a supramolecular DNA-protein complex that compacts eukaryotic genomes and regulates their accessibility and functions. Dynamically disordered histone H3 N-terminal tails are among key chromatin regulatory components. Here, we used high-resolution-magic-angle-spinning NMR measurements of backbone amide

Indexed as

ChromatinDNAHistonesMagnetic Resonance SpectroscopyModels, MolecularProtein ConformationStatic ElectricityChromatinDNAHistones

Identifiers

PMID34184895
PMCPMC8788308
OpenAlexW3176130138

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.