Mechanism of O-Atom Transfer from Nitrite: Nitric Oxide Release at Copper(II).

Molly Stauffer, Zeinab Sakhaei, Christine Greene, Pokhraj Ghosh, Jeffery A Bertke, Timothy H Warren

Abstract read

In one paragraph

Article in Inorganic chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it

0cells of the map it votes in

5citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

Reductive and Oxidative Transformations of Nitrite at Nickel(II): Insights into the Generation, Electronic Structure, and Reactivity of {NiNO}JACS Au · 2026
Article
Stepwise Nitrate → Dinitrogen Transformation Mediated by a Series of Synthetic Heme/Cobalt and Heme/Copper Assemblies: Modeling Denitrification with CytochromeJACS Au · 2025
Article
Synthetically Reversible, Proton-Mediated Nitrite N-O Bond Cleavage at a Dicopper Site.Journal of the American Chemical Society · 2024
Article
Thiol and HJournal of the American Chemical Society · 2023
Article
NO Coupling at Copper toJournal of the American Chemical Society · 2022
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Molly StaufferDepartment of Chemistry, Georgetown University, Box 571227-1227, Washington, D.C. 20057, United States.

Zeinab SakhaeiDepartment of Chemistry, Georgetown University, Box 571227-1227, Washington, D.C. 20057, United States.

Christine GreeneDepartment of Chemistry, Georgetown University, Box 571227-1227, Washington, D.C. 20057, United States.

Pokhraj GhoshDepartment of Chemistry, Georgetown University, Box 571227-1227, Washington, D.C. 20057, United States.

Jeffery A BertkeDepartment of Chemistry, Georgetown University, Box 571227-1227, Washington, D.C. 20057, United States.ORCID https://orcid.org/0000-0002-3419-5163

Timothy H WarrenDepartment of Chemistry, Georgetown University, Box 571227-1227, Washington, D.C. 20057, United States.ORCID https://orcid.org/0000-0001-9217-8890

Funding

Nitric Oxide Signaling Chemistry at Non-Heme SitesR01GM126205 · NIGMS · GEORGETOWN UNIVERSITY · PI WARREN, TIMOTHY H · 2017 to 2020

$1.2M

NIGMS NIH HHS R01 GM126205

6 · The paper itself

Abstract

Nitric oxide (NO) is a key signaling molecule in health and disease. While nitrite acts as a reservoir of NO activity, mechanisms for NO release require further understanding. A series of electronically varied β-diketiminatocopper(II) nitrite complexes [Cu

Identifiers

PMID34184870

DOI10.1021/acs.inorgchem.1c00625

PMCPMC9534358

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.