Evidence map›Paper›PMID 34184557›Full record

ArticleClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

Genetic and Clinical Predictors of Left Atrial Thrombus: A Single Center Case-Control Study.

Adrian Springer, Ruben Schleberger, Florian Oyen, Boris A Hoffmann, Stephan Willems, Christian Meyer, Florian Langer, Renate B Schnabel, Paulus Kirchhof, Reinhard Schneppenheim and 1 more

Abstract read
In one paragraph

Article in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Adrian SpringerDepartment of Cardiology, University Heart and Vascular Center, Hamburg, Germany.
Ruben SchlebergerDepartment of Cardiology, University Heart and Vascular Center, Hamburg, Germany.
Florian OyenDepartment of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Boris A HoffmannDepartment of Cardiology, University Heart and Vascular Center, Hamburg, Germany.
Stephan WillemsDepartment of Cardiology, University Heart and Vascular Center, Hamburg, Germany.
Christian MeyerDepartment of Cardiology, University Heart and Vascular Center, Hamburg, Germany.
Florian LangerDepartment of Oncology and Hematology, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Renate B SchnabelDepartment of Cardiology, University Heart and Vascular Center, Hamburg, Germany.
Paulus KirchhofDepartment of Cardiology, University Heart and Vascular Center, Hamburg, Germany.
Reinhard SchneppenheimDepartment of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Marc D LemoineDepartment of Cardiology, University Heart and Vascular Center, Hamburg, Germany.ORCID https://orcid.org/0000-0002-3799-7962

Funding

British Heart Foundation PG/17/30/32961British Heart Foundation PG/20/22/35093
6 · The paper itself

Abstract

Left atrial (LA) thrombus formation is the presumed origin of thromboembolic complications in patients with atrial fibrillation (AF). Beyond clinical risk factors, the factors causing formation of LA thrombi are not well known. In this case-control study, we analyzed clinical characteristics and genetic thrombophilia markers (factor V Leiden (FVL), prothrombin G20210A (FIIV), Tyr2561 variant of von Willebrand factor (VWF-V)) in 42 patients with AF and LA thrombus (LAT) and in 68 control patients with AF without LAT (CTR). Patients with LAT had more clinical conditions predisposing to stroke (mean CHA

Indexed as

AgedAtrial FibrillationCase-Control StudiesEchocardiography, TransesophagealHumansRisk AssessmentThrombosisatrial fibrillationbiomarkersechocardiographygenetic association studiesleft atrial thrombustransesophageal echocardiographyvon willebrand factor

Identifiers

PMID34184557
PMCPMC8246465

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.