ArticleJournal of the American Heart Association2021
Prevalence and Course of Depression During the First Year After Mild to Moderate Stroke.
Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Ranking psychological interventions for post-stroke depression: A systematic review and network meta-analysis.Psychological medicine · 2026Pooled it
- Functional and Cognitive Occupational Therapy (FaCInternational journal of environmental research and public health · 2023Trial
- Depressive Symptoms After Mechanical Thrombectomy in Ischaemic Stroke: A Longitudinal Descriptive Study with Gender Differences.Healthcare (Basel, Switzerland) · 2026Article
- Current Progress of Mechanisms Underlying Post-Stroke Depression and Music Therapy.Chinese journal of integrative medicine · 2026Review
- Optimizing Identification and Management of Depression in Neurological Diseases: A Narrative Review and Expert Perspective.Neuropsychiatric disease and treatment · 2026Article
- Neurorehabilitation needs a qualitative perspective: a case exemplar from stroke recovery and rehabilitation.Frontiers in human neuroscience · 2026Article
- Person-Centered Approaches for Identifying Subgroups of Post-Stroke Depression: A Systematic Review of Observational Studies.Patient preference and adherence · 2026Review
- Temporal Relationships Between Depression, Self-Efficacy, and Physical Activity in Individuals With Stroke.Archives of rehabilitation research and clinical translation · 2025Article
- Network analysis of mutuality and depression symptoms in stroke survivors in China.Scientific reports · 2025Article
- Comparative Study on the Neuroprotective Effects of Perindopril and Benazepril in Experimentally-induced Chronic Mild Stress in Rats.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2025Article
- Anxiety and depression one year after the first stroke among Lebanese survivors: proportions, changes, and predictors.BMC psychiatry · 2025Article
- Depressive Symptoms Are Associated With Reduced Unsupervised Training Engagement in Inpatients With Subacute Stroke: A Secondary Data Analysis Study.Archives of rehabilitation research and clinical translation · 2025Article
- Protocol for a randomized controlled trial evaluating the artificial intelligence health education accurately linking system in patients with mild-to-moderate stroke.Frontiers in neurology · 2025Article
- Large-scale lesion symptom mapping of depression identifies brain regions for risk and resilience.Brain : a journal of neurology · 2023Article
- Sleep and Stroke: Opening Our Eyes to Current Knowledge of a Key Relationship.Current neurology and neuroscience reports · 2022Review
- Integrating Metabolomics and Network Analysis for Exploring the Mechanism Underlying the Antidepressant Activity of Paeoniflorin in Rats With CUMS-Induced Depression.Frontiers in pharmacology · 2022Article
- Prevalence and Course of Depression During the First Year After Mild to Moderate Stroke.Journal of the American Heart Association · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Background This study examined the prevalence and longitudinal course of depression during the first year after mild to moderate stroke. Methods and Results We identified patients with mild to moderate ischemic stroke or intracerebral hemorrhage (National Institutes of Health Stroke Scale score <16) and at least 1 depression assessment at 3, 6, or 12 months after stroke (n=648, 542, and 533, respectively) from the Brain Attack Surveillance in Corpus Christi project (2014-2016). Latent transition analysis was used to examine temporal profiles of depressive symptoms assessed by the 8-item Patient Health Questionnaire between 3 and 12 months after stroke. Mean age was 65.6 years, 49.4% were women, and 56.7% were Mexican Americans. The prevalence of depression after stroke was 35.3% at 3 months, decreased to 24.9% at 6 months, and remained stable at 25.7% at 12 months. Approximately half of the participants classified as having depression at 3 or 6 months showed clinical improvement at the next assessment. Subgroups with distinct patterns of depressive symptoms were identified, including mild/no symptoms, predominant sleep disturbance and fatigue symptoms, affective symptoms, and severe/all symptoms. A majority of participants with mild/no symptoms retained this symptom pattern over time. The probability of transitioning to mild/no symptoms was higher before 6 months compared with the later period, and severe symptoms were more likely to persist after 6 months compared with the earlier period. Conclusions The observed dynamics of depressive symptoms suggest that depression after stroke tends to persist after 6 months among patients with mild to moderate stroke and should be continually monitored and appropriately managed.
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