Evidence map›Paper›PMID 34184428›Full record

ArticleESC heart failure2021

Multiparameter diagnostic sensor measurements in heart failure patients presenting with SARS-CoV-2 infection.

Roy S Gardner, Robert C Capodilupo, Rezwan Ahmed, Craig M Stolen, Qi An, Viktoria Averina, Adrian F Hernandez, John P Boehmer

Open access · goldAbstract read
In one paragraph

Article in ESC heart failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Roy S GardnerGolden Jubilee National Hospital, Clydebank, Glasgow, UK.
Robert C CapodilupoNew England Heart and Vascular Institute, Catholic Medical Center, Manchester, NH, USA.
Rezwan AhmedBoston Scientific, Arden Hills, MN, USA.
Craig M StolenBoston Scientific, Arden Hills, MN, USA.
Qi AnBoston Scientific, Arden Hills, MN, USA.
Viktoria AverinaBoston Scientific, Arden Hills, MN, USA.
Adrian F HernandezDuke University School of Medicine, Durham, NC, USA.
John P BoehmerPenn State Milton S Hershey Medical Center, Hershey, PA, USA.
Boston Scientific (United States) · USCatholic Medical Center · USDuke University · USGolden Jubilee National Hospital · GBPenn State Milton S. Hershey Medical Center · US

Funding

Boston Scientific Corporation
6 · The paper itself

Abstract

aimsImplantable device-based sensor measurements including heart sounds, markers of ventilation, and thoracic impedance have been shown to predict heart failure (HF) hospitalizations. We sought to assess how these parameters changed prior to COVID-19 (Cov-19) and how these compared with those presenting with decompensated HF or pneumonia. METHODS AND

resultsThis retrospective analysis explores patterns of changes in daily measurements by implantable sensors in 10 patients with Cov-19 and compares these findings with those observed prior to HF (n = 88) and pneumonia (n = 12) hospitalizations from the MultiSENSE, PREEMPT-HF, and MANAGE-HF trials. The earliest sensor changes prior to Cov-19 were observed in respiratory rate (6 days) and temperature (5 days). There was a three-fold to four-fold greater increase in respiratory rate, rapid shallow breathing index, and night heart rate compared with those presenting with HF or pneumonia. Furthermore, activity levels fell more in those presenting with Cov-19, a change that was often sustained for some time. In contrast, there were no significant changes in 1st or 3rd heart sound (S

conclusionsMulti-sensor device diagnostics may provide early detection of Cov-19, distinguishable from worsening HF by an extreme and fast rise in respiratory rate along with no changes in S3.

Indexed as

COVID-19Heart FailureHospitalizationHumansRetrospective StudiesSARS-CoV-2Ambulatory monitoringCOVID-19CRTHeart failureICDSARS-Cov-2

Identifiers

PMID34184428
PMCPMC8426935
OpenAlexW3173822447

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.