Evidence map›Paper›PMID 34184214›Full record

ReviewCardiology and therapy2021

Thrombosis Prevention and Anticoagulation Management in the Pediatric Patient with Congenital Heart Disease.

Eman Abdelghani, Clifford L Cua, Jean Giver, Vilmarie Rodriguez

Open access · goldAbstract readReview
In one paragraph

Review in Cardiology and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
  2. Heparin Resistance - A Reality or Fallacy.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2026
    Article
  3. Article
  4. Thrombus formation in neonates and early infants undergoing congenital heart surgery.International journal of cardiology. Congenital heart disease · 2025
    Article
  5. Post-Pyloric Administration of Rivaroxaban With Therapeutic Monitoring in Pediatric Cardiac Patients: Experience in 3 Patients.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Inferior vena cava thrombosis-rope ladder sign.Wiener medizinische Wochenschrift (1946) · 2023
    Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Eman AbdelghaniDivision of Pediatric Hematology/Oncology, Nationwide Children's Hospital, Columbus, OH, USA.
Clifford L CuaHeart Center, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH, USA. Clifford.Cua@nationwidechildrens.org.
Jean GiverDivision of Pediatric Hematology/Oncology, Nationwide Children's Hospital, Columbus, OH, USA.
Vilmarie RodriguezDivision of Pediatric Hematology/Oncology, Nationwide Children's Hospital, Columbus, OH, USA.
Nationwide Children's Hospital · USThe Ohio State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thrombosis is one of the most frequent complications affecting children with congenital heart disease (CHD). Palliative and reparative cardiac surgeries are some of the main players contributing to the thrombosis risk in this patient population. Additional risk factors related to the CHD itself (e.g., cardiac dysfunction, arrhythmias, and polycythemia in cyanotic cardiac disorders) can contribute to thrombogenicity alone or combined with other factors. Thrombotic complications have been recognized as a significant cause of morbidity and mortality in this patient population. Here, we provide an overview of the pathophysiology and risk factors for thrombosis as well as the indications for and use of different anticoagulation, antiplatelet, and thrombolytic agents. In addition, we describe some of most common thrombotic complications and their management in the pediatric CHD population.

Indexed as

AnticoagulationAspirinCongenital heart diseaseHeparinThrombosisWarfarin

Identifiers

PMID34184214
PMCPMC8555036
OpenAlexW3174909777

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.