Evidence map›Paper›PMID 34184177›Full record

ArticleNeurocritical care2021

COVID-19 and the Pediatric Nervous System: Global Collaboration to Meet a Global Need.

Michelle Elena Schober, Courtney Leigh Robertson, Mark Stephen Wainwright, Juan David Roa, Ericka Linn Fink

Open access · bronzeAbstract readEditorial
In one paragraph

Article in Neurocritical care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Neurological effects of COVID-19 in infants and children.Developmental medicine and child neurology · 2022
    Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

Michelle Elena SchoberDivision of Critical Care, Department of Pediatrics, University of Utah, Salt Lake City, UT, 84132, USA. michelle.schober@hsc.utah.edu.ORCID http://orcid.org/0000-0002-7812-2441
Courtney Leigh RobertsonDepartments of Anesthesiology and Critical Care Medicine and Pediatrics, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Mark Stephen WainwrightDepartment of Pediatric Neurology, Seattle Children's Hospital, Seattle, WA, USA.
Juan David RoaDivision of Critical Care, Department of Pediatrics, Universidad Nacional de Colombia and Fundación Universitaria de Ciencias de la Salud, Bogotá, Colombia.
Ericka Linn FinkDivision of Pediatric Critical Care Medicine, Department of Pediatric Neurology and Critical Care, and Safar Center for Resuscitation Research, University of Pittsburgh Medical Center Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.
Children's Hospital of Pittsburgh · USJohns Hopkins University · USSeattle Children's Hospital · USUniversidad Nacional de Colombia · COUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coronavirus disease 2019 (COVID-19) pandemic has affected mortality and morbidity across all ages, including children. It is now known that neurological manifestations of COVID-19, ranging from headaches to stroke, may involve the central and/or peripheral nervous system at any age. Neurologic involvement is also noted in the multisystem inflammatory syndrome in children, a pediatric condition that occurs weeks after infection with the causative virus of COVID-19, severe acute respiratory syndrome coronavirus 2. Knowledge about mechanisms of neurologic disease is scarce but rapidly growing. COVID-19 neurologic manifestations may have particularly adverse impacts on the developing brain. Emerging data suggest a cohort of patients with COVID-19 will have longitudinal illness affecting their cognitive, physical, and emotional health, but little is known about the long-term impact on affected children and their families. Pediatric collaboratives have begun to provide important initial information on neuroimaging manifestations and the incidence of ischemic stroke in children with COVID 19. The Global Consortium Study of Neurologic Dysfunction in COVID-19-Pediatrics, a multinational collaborative, is working to improve understanding of the epidemiology, mechanisms of neurological manifestations, and the long-term implications of COVID-19 in children and their families.

Indexed as

COVID-19Nervous System DiseasesPediatricsChildHumansNervous SystemSARS-CoV-2Systemic Inflammatory Response SyndromeChild developmentCOVID-19Neurological manifestationsPediatrics

Identifiers

PMID34184177
PMCPMC8238033
OpenAlexW3177204043

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.