Evidence map›Paper›PMID 34184142›Full record

ArticleJournal of autism and developmental disorders2022

Altered Cerebellum Spontaneous Activity in Juvenile Autism Spectrum Disorders Associated with Clinical Traits.

Jinglun Li, Xiu Chen, Ruwen Zheng, Ai Chen, Yan Zhou, Jianghai Ruan

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of autism and developmental disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Jinglun LiDepartment of Neurology, The Affiliated Hospital of Southwest Medical University, Taiping Street No.25, Luzhou, 646000, China.
Xiu ChenDepartment of Neurology, The Affiliated Hospital of Southwest Medical University, Taiping Street No.25, Luzhou, 646000, China.
Ruwen ZhengDepartment of Acupuncture and Moxibustion, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, 100071, China.
Ai ChenDepartment of Pediatric, Sichuan Provincial Hospital for Women and Children, Chengdu, 610041, China.
Yan ZhouDepartment of Neurology, The Affiliated Hospital of Southwest Medical University, Taiping Street No.25, Luzhou, 646000, China.
Jianghai RuanDepartment of Neurology, The Affiliated Hospital of Southwest Medical University, Taiping Street No.25, Luzhou, 646000, China. jianghai.ruan@swmu.edu.cn.ORCID http://orcid.org/0000-0002-0915-292X
Affiliated Hospital of Southwest Medical University · CNBeijing University of Chinese Medicine · CNChengdu Women's and Children's Central Hospital · CNSouthwest Medical University · CN

Funding

Young Scientists Fund 81804198
6 · The paper itself

Abstract

Autism spectrum disorder (ASD) is a neurodevelopmental disorder. The associations between the cerebellum and clinical traits remain unclear. We performed amplitude of low-frequency fluctuation (ALFF) analysis to explore the associations between spontaneous brain activity and clinical traits. 361 juvenile ASD patients were included from the ABIDEII database. In the ASD group, the mean ALFF values of cerebellum 4 5 were correlated with SRS awareness and communication. The mean ALFF values of cerebellum 6 and vermis 4 5 were both positively correlated with SRS total, awareness, communication, and motivation. In contrast, the mean ALFF values of vermis 1 2 were negatively correlated with SRS total, awareness, and mannerisms. Our study suggests a role of the cerebellum in functional impairments in ASD.

Indexed as

Autism Spectrum DisorderBrainBrain MappingCase-Control StudiesCerebellumHumansMagnetic Resonance ImagingPhenotypeAmplitude of low-frequency fluctuationsAutism spectrum disordersCerebellumFunctional magnetic resonance imaging

Identifiers

PMID34184142
OpenAlexW3176459982

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.