Evidence map›Paper›PMID 34184125›Full record

ArticleJournal of neurology2022

Safety and outcome of mechanical thrombectomy in ischaemic stroke related to carotid artery dissection.

A Karam, N Bricout, M Khyeng, C Cordonnier, X Leclerc, H Henon, B Casolla

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Article in Journal of neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

A KaramU1172 - LilNCog - Lille Neuroscience and Cognition, University of Lille, Inserm, CHU Lille, 27023, Lille, France.
N BricoutDepartment of Neuroradiology, Roger Salengro Hospital, CHU Lille, University of Lille, 59037, Lille, France.
M KhyengULR 2694-METRICS: Évaluation Des Technologies de Santé Et Des Pratiques Médicales, Univ. Lille, CHU Lille, 59000, Lille, France.
C CordonnierU1172 - LilNCog - Lille Neuroscience and Cognition, University of Lille, Inserm, CHU Lille, 27023, Lille, France.
X LeclercDepartment of Neuroradiology, Roger Salengro Hospital, CHU Lille, University of Lille, 59037, Lille, France.
H HenonU1172 - LilNCog - Lille Neuroscience and Cognition, University of Lille, Inserm, CHU Lille, 27023, Lille, France.
B CasollaU1172 - LilNCog - Lille Neuroscience and Cognition, University of Lille, Inserm, CHU Lille, 27023, Lille, France. b.casolla@gmail.com.ORCID http://orcid.org/0000-0003-4199-995X
Inserm · FRUniversité de Lille · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe net clinical benefit of mechanical thrombectomy (MT) in patients with anterior circulation ischaemic stroke associated with large vessel occlusion (AIS-LVO) related to carotid artery dissection (CAD) is uncertain. The aim of the study was to investigate the safety and clinical outcomes of patients treated by MT for a CAD-related stroke.

methodsWe included consecutive patients with AIS-LVO treated by MT between 1st 2015 and January 1st 2020 at Lille University Hospital. We compared the safety and clinical outcomes, including successful recanalisation, defined as a modified thrombolysis in cerebral infarction (mTICI) ≥ 2b and favourable functional outcome at 3 months (defined as a modified Rankin Scale (mRS) ≤ 2 or equal to pre-stroke), in patients with CAD-related stroke versus patients with other aetiologies.

resultsWe included 1422 patients, among them, 43 patients with CAD-related AIS-LVO were matched to 86 patients with other aetiologies. Procedural complications, sICH (ECASS-3 criteria) and mortality rates were similar in the two groups (OR 0.85, 95% CI 0.21-3.49, p = 0.82; OR 1.54 95% CI 0.33-2.79, p = 0.58; OR 0.18 95% CI 0.02-1.46, p = 0.11, respectively), as well as the rates of intracranial angiographic successful recanalisation and favourable functional outcome (OR 0.67 (95% CI 0.26-1.73, p = 0.41; OR 1.26 (95% CI 0.61-2.64, p = 0.53). In patients with CAD-related stroke, intracranial angiographic success after MT was significantly associated with favourable functional outcome.

conclusionsIn patients with AIS-LVO related to CAD, safety profiles and clinical outcomes after MT are similar compared to matched patients with other stroke aetiologies.

Indexed as

Brain IschemiaIschemic StrokeStrokeCarotid ArteriesDissectionHumansRetrospective StudiesThrombectomyTreatment OutcomeCarotid dissectionLarge vessel occlusionMatchingMechanical thrombectomyStroke

Identifiers

PMID34184125
OpenAlexW3174194983

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.