ArticleMikrochimica acta2021
CuO/Cu-MOF nanocomposite for highly sensitive detection of nitric oxide released from living cells using an electrochemical microfluidic device.
Article in Mikrochimica acta, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 44 citations in OpenAlex.
- Smart Textile: Electrohydrodynamic Jet Printing of Ionic Liquid-Functionalized CuACS applied materials & interfaces · 2025Article
- Article
- CuO-ZIF-8 modified electrode surface as a new electrochemical sensing platform for detection of free chlorine in aqueous solution.Scientific reports · 2024Article
- Nanoscale designing of metal organic framework moieties as efficient tools for environmental decontamination.Nanoscale advances · 2023Review
- Nitric Oxide-Releasing Platforms for Treating Cardiovascular Disease.Pharmaceutics · 2022Review
- GNP-CeOMikrochimica acta · 2021Article
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
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Abstract
The integration of large surface area and high catalytic profiles of Cu-MOF and CuO nanoparticles is described toward electrochemical sensing of nitric oxide (NO) in a microfluidic platform. The CuO/Cu-MOF nanocomposite was prepared through hydrothermal method, and its formation was confirmed by scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray powder diffraction (XRD), X-ray photoelectron spectroscopy (XPS), and energy-dispersive X-ray spectroscopy (EDS). The CuO/Cu-MOF nanostructured modified Au electrodes enabled electrocatalytic NO oxidation at 0.6 V vs. reference electrode, demonstrating linear response over a broad concentration range of 0.03-1 μM and 1-500 μM with a detection limit of 7.8 nM. The interference effect of organic molecules and common ions was negligible, and the sensing system demonstrated excellent stability. Finally, an electrochemical microfluidic NO sensor was developed to detect of NO released from cancer cells, which were stimulated by L-arginine. Furthermore, in the presence of Fe
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