Evidence map›Paper›PMID 34184102›Full record

ArticleAnalytical and bioanalytical chemistry2021

Assessment of serum total 25-hydroxyvitamin D assay commutability of Standard Reference Materials and College of American Pathologists Accuracy-Based Vitamin D (ABVD) Scheme and Vitamin D External Quality Assessment Scheme (DEQAS) materials: Vitamin D Standardization Program (VDSP) Commutability Study 2.

Johanna E Camara, Stephen A Wise, Andrew N Hoofnagle, Emma L Williams, Graham D Carter, Julia Jones, Carolyn Q Burdette, Grace Hahm, Federica Nalin, Adam J Kuszak and 40 more

Registry-linked trialAbstract read
In one paragraph

Article in Analytical and bioanalytical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06753279 (Clinical Significance of Leukocyte Cell Population Data in Patients With Myeloproliferative Neoplasms), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06753279 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Clinical Significance of Leukocyte Cell Population Data in Patients With Myeloproliferative Neoplasms (MPNs)

TypeobservationalSponsorAssiut UniversityRan2025 to 2026Enrolled80ConditionsMyeloproliferative Neoplasms (MPNs)
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Determination of 24,25-dihydroxyvitamin DThe Journal of steroid biochemistry and molecular biology · 2023
    Article
  7. Vitamin D: marker, measurand & measurement.Endocrine connections · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

50 authors.

Johanna E CamaraChemical Sciences Division, National Institute of Standards and Technology (NIST), Gaithersburg, MD, 20899, USA.
Stephen A WiseScientist Emeritus, National Institute of Standards and Technology (NIST), Gaithersburg, MD, 20899, USA. stephen.wise@nih.gov.
Andrew N HoofnagleDepartment of Laboratory Medicine, University of Washington, Seattle, WA, 98185, USA.
Emma L WilliamsImperial Healthcare NHS Trust, London, W6 8RF, UK.
Graham D CarterImperial Healthcare NHS Trust, London, W6 8RF, UK.
Julia JonesImperial Healthcare NHS Trust, London, W6 8RF, UK.
Carolyn Q BurdetteChemical Sciences Division, National Institute of Standards and Technology (NIST), Gaithersburg, MD, 20899, USA.
Grace HahmChemical Sciences Division, National Institute of Standards and Technology (NIST), Gaithersburg, MD, 20899, USA.
Federica NalinChemical Sciences Division, National Institute of Standards and Technology (NIST), Gaithersburg, MD, 20899, USA.
Adam J KuszakOffice of Dietary Supplements (ODS), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
Joyce MerkelOffice of Dietary Supplements (ODS), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
Ramón A Durazo-ArvizuBiostatistics Core, The Sabin Research Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90027, USA.
Pierre LukasClinical Chemistry, University of Liège, CHU de Liège, 4000, Liège, Belgium.
Étienne CavalierClinical Chemistry, University of Liège, CHU de Liège, 4000, Liège, Belgium.
Christian PoppAbbott Laboratories, ADD Wiesbaden Abbott GmbH, 65205, Wiesbaden, Germany.
Christian BeckertAbbott Laboratories, ADD Wiesbaden Abbott GmbH, 65205, Wiesbaden, Germany.
Jan SchultessAbbott Laboratories, ADD Wiesbaden Abbott GmbH, 65205, Wiesbaden, Germany.
Glen Van SlootenAwareness Technology, Inc., Palm City, FL, 34990, USA.
Carole TourneurbioMérieux, 69280, Marcy-l'Étoile, France.
Camille PeasebioMérieux, 69280, Marcy-l'Étoile, France.
Ravi KaulClinical Diagnostics, Bio-Rad Laboratories, Clinical Diagnostics, Hercules, CA, 94547, USA.
Alfredo VillarrealClinical Diagnostics, Bio-Rad Laboratories, Clinical Diagnostics, Hercules, CA, 94547, USA.
Fiona IvisonCentral Manchester Foundation Trust, Manchester, M13 9WL, UK.
Ralf FischerChromsystems Instruments & Chemicals GmbH, 82166, Gräfelfing, Germany.
Jody M W van den OuwelandCanisius Wilhelmina Hospital (CWZ), 6532 SZ, Nijmegen, The Netherlands.
Chung S HoBiomedical Mass Spectrometry Unit, Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, 999077, Hong Kong.
Emmett W K LawBiomedical Mass Spectrometry Unit, Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, 999077, Hong Kong.
Jean-Nicolas SimardEndoceutics Inc., Québec, G1P 4P5, Canada.
Renaud GonthierEndoceutics Inc., Québec, G1P 4P5, Canada.
Brett HolmquistLabCorp Specialty Testing Group, Endocrine Sciences, Agoura Hills, CA, 91301, USA.
Marcelo Cidade BatistaClinical Lab, Hospital Israelita Albert Einstein, São Paulo, 05652-900, Brazil.
Heather PhamImmunodiagnostic Systems (IDS), Boldon, NE35 9PD, UK.
Alex BennettImmunodiagnostic Systems (IDS), Boldon, NE35 9PD, UK.
Sarah MeadowsMedical Research Council (MRC) Elsie Widdowson Laboratory (closed Dec. 2018), Cambridge, CB2 0SL, UK.
Lorna CoxMedical Research Council (MRC) Elsie Widdowson Laboratory (closed Dec. 2018), Cambridge, CB2 0SL, UK.
Eugene JansenNational Institute of Public Health and the Environment (RIVM), 3720 BA, Bilthoven, The Netherlands.
Dilshad Ahmed KhanNational University of Medical Sciences (NUMS), Rawalpindi, Punjab, 46000, Pakistan.
Kimberly RobyakCollege of Medicine, Penn State University, Hershey, PA, 17033, USA.
Michael H CreerCollege of Medicine, Penn State University, Hershey, PA, 17033, USA.
Mark KilbaneClinical Chemistry, St. Vincent's University Hospital, Elm Park, Dublin 4, D04 T6F4, Ireland.
Patrick J TwomeyClinical Chemistry, St. Vincent's University Hospital, Elm Park, Dublin 4, D04 T6F4, Ireland.
James FreemanSiemens-Healthineers, Tarrytown, NY, 10591, USA.
Neil ParkerSiemens-Healthineers, Tarrytown, NY, 10591, USA.
Jinyun YuanSNIBE, Shenzhen, 518122, People's Republic of China.
Robert FitzgeraldUniversity of California at San Diego, Health Clinical Laboratories, La Jolla, CA, 92093, USA.
Sohail MushtaqUniversity of Chester, Chester, CH1 4BJ, UK.
Michael W ClarkeMetabolomics Australia, Centre for Microscopy, Characterisation and Analysis, The University of Western Australia, Perth, WA, 6009, Australia.
Norma BreenWaters Technologies Ireland Ltd., Wexford, Y35 D431, Ireland.
Christine SimpsonSchool of Medicine, Yale University, New Haven, CT, 06510, USA.
Christopher T SemposOffice of Dietary Supplements (ODS), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.

Funding

Intramural NIH HHS Z99 OD999999
6 · The paper itself

Abstract

An interlaboratory study was conducted through the Vitamin D Standardization Program (VDSP) to assess commutability of Standard Reference Materials® (SRMs) and proficiency testing/external quality assessment (PT/EQA) samples for determination of serum total 25-hydroxyvitamin D [25(OH)D] using ligand binding assays and liquid chromatography-tandem mass spectrometry (LC-MS/MS). A set of 50 single-donor serum samples were assigned target values for 25-hydroxyvitamin D

Indexed as

HumansReference StandardsSocieties, MedicalSpecimen HandlingVitamin D25-hydroxyvitamin DVitamin D25-Hydroxyvitamin D225-Hydroxyvitamin D3Ligand binding assayLiquid chromatography-tandem mass spectrometry (LC-MS/MS)Total 25-hydroxyvitamin DVitamin D Standardization Program (VDSP)

Identifiers

PMID34184102
PMCPMC8431775

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.