ArticleOpen forum infectious diseases2021
Diagnostic Utility of a Ferritin-to-Procalcitonin Ratio to Differentiate Patients With COVID-19 From Those With Bacterial Pneumonia: A Multicenter Study.
Article in Open forum infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 14 citations in OpenAlex.
- Distinguishing Between Bacterial and Viral Community-Acquired Pneumonia in Hospitalized Adults: The Importance of Clinical, Laboratory, and Imaging Findings.Pulmonary medicine · 2026Article
- Machine learning predictive modeling of the persistence of post-Covid19 disorders: Loss of smell and taste as case studies.Heliyon · 2024Article
- Incidence and risk factors for clinically confirmed secondary bacterial infections in patients hospitalized for coronavirus disease 2019 (COVID-19).Infection control and hospital epidemiology · 2023Article
- Review
- The detrimental impact of elevated Ferritin to Iron ratio on in-hospital prognosis of patients with COVID-19.Expert review of molecular diagnostics · 2022Article
- Selective digestive decontamination and COVID-19: Uncertainty in a moving area.Anaesthesia, critical care & pain medicine · 2022Article
- COVID-19 and antimicrobial stewardship: lessons learned, best practices, and future implications.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021Review
- Serum ferritin levels in inflammation: a retrospective comparative analysis between COVID-19 and emergency surgical non-COVID-19 patients.World journal of emergency surgery : WJES · 2021Observational
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Authors and funding
15 authors at 6 institutions in 4 countries.
Funding
Abstract
backgroundThere is an urgent need for accurate, rapid, inexpensive biomarkers that can differentiate coronavirus disease 2019 (COVID-19) from bacterial pneumonia. We assess the role of the ferritin-to-procalcitonin (F/P) ratio to classify pneumonia cases into those due to COVID-19 vs those due to bacterial pathogens.
methodsThis multicenter case-control study compared patients with COVID-19 with those with bacterial pneumonia, admitted between March 1 and May 31, 2020. Patients with COVID-19 and bacterial pneumonia co-infection were excluded. The F/P in patients with COVID-19 vs with bacterial pneumonia were compared. Receiver operating characteristic curve analysis determined the sensitivity and specificity of various cutoff F/P values for COVID-19 vs bacterial pneumonia.
resultsA total of 242 COVID-19 pneumonia cases and 34 bacterial pneumonia controls were included. Patients with COVID-19 pneumonia had a lower mean age (57.1 vs 64.4 years;
conclusionsAn F/P ≥877 increases the likelihood of COVID-19 pneumonia compared with bacterial pneumonia.
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