ArticleIranian journal of public health2021
Epidemiological Characteristics of Hand, Foot, and Mouth Disease Outbreaks in Qingdao, 2009-2018.
Article in Iranian journal of public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 10 citations in OpenAlex.
- The Etiological Characteristics of Hand, Foot, and Mouth Disease in Yuyao, China, 2010-2023.Iranian journal of public health · 2025Article
- Risk Factors for Hand, Foot and Mouth Disease Reinfection in Qingdao, China, from 2014 to 2022.Iranian journal of public health · 2025Article
- Impact of kindergarten structures on the dynamics of hand, foot, and mouth disease and the effects of intervention strategies: an agent-based modeling study.BMC medicine · 2025Article
- The need for development of other enterovirus vaccines in addition to EV-A71 vaccine.Human vaccines & immunotherapeutics · 2024Article
- Observational
- Preclinical safety evaluation of a bivalent inactivated EV71-CA16 vaccine in mice immunized intradermally.Human vaccines & immunotherapeutics · 2023Article
- Phylogeographic dynamics and molecular characteristics ofFrontiers in microbiology · 2023Article
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Authors and funding
7 authors at 2 institutions in 1 country.
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Abstract
backgroundIn China, hand, foot, and mouth disease (HFMD) outbreaks have become an important issue recent years. We analyzed the epidemiological characteristics of HFMD outbreaks in Qingdao during 2009-2018, and provided evidences for prevention and control of the disease.
methodsData were analyzed by descriptive analysis and correlation analysis, and throat swabs were detected for enterovirus RNA using RT-PCR.
resultsOverall, 116 HFMD outbreaks were reported in Qingdao during 2009-2018, with the epidemic of the outbreaks exhibiting a decreasing tendency. The characteristics of outbreaks presented two patterns, including two-peak pattern and rural area to urban-rural fringe area to urban areas pattern. Male patients were predominant in these outbreaks. The location of the outbreaks changed from nursery to community. Non-EV71/CA16 enteroviruses were gradually becoming predominant enteroviruses serotypes. The durations of outbreaks were positively correlated with response times and the number of cases.
conclusionThe epidemiological characteristics analysis of HFMD outbreaks could provide a scientific basis for the prevention and control the disease. Reporting and handling promptly are the keys to control epidemic outbreaks of HFMD.
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