Evidence map›Paper›PMID 34183867›Full record

ArticleNature neuroscience2021

Enhanced hippocampal theta rhythmicity and emergence of eta oscillation in virtual reality.

Karen Safaryan, Mayank R Mehta

Abstract read
PubMed Publisher
In one paragraph

Article in Nature neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
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  12. Extended reality for biomedicine.Nature reviews. Methods primers · 2023
    Article
  13. Review
  14. Naturalistic neuroscience and virtual reality.Frontiers in systems neuroscience · 2022
    Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Karen SafaryanDepartment of Physics and Astronomy, University of California, Los Angeles, Los Angeles, CA, USA. safaryan@ucla.edu.ORCID http://orcid.org/0000-0001-8665-4707
Mayank R MehtaDepartment of Physics and Astronomy, University of California, Los Angeles, Los Angeles, CA, USA. mayankmehta@ucla.edu.ORCID http://orcid.org/0000-0003-2005-2468
University of California, Los Angeles · US

Funding

1/2 Cross modal integration of molecular and physiological networks in ASDU01MH115746 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GESCHWIND, DANIEL H, MEHTA, MAYANK R · 2017 to 2021
$5.3M
NIMH NIH HHS U01 MH115746
6 · The paper itself

Abstract

Hippocampal theta rhythm is a therapeutic target because of its vital role in neuroplasticity, learning and memory. Curiously, theta differs across species. Here we show that theta rhythmicity is greatly amplified when rats run in virtual reality. A novel eta rhythm emerged in the CA1 cell layer, primarily in interneurons. Thus, multisensory experience governs hippocampal rhythms. Virtual reality can be used to boost or control brain rhythms and to alter neural dynamics, wiring and plasticity.

Indexed as

Virtual RealityAnimalsBrain WavesHippocampusMaleRatsRats, Long-Evans

Identifiers

PMID34183867
OpenAlexW3176996897

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.