ArticleNature biotechnology2021
Fully implantable and bioresorbable cardiac pacemakers without leads or batteries.
Article in Nature biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 124 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
124 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Epicardial Versus Endocardial Pacing in Paediatric Patients with Atrioventricular Block or Sinus Node Dysfunction: A Systematic Review and Meta-analysis.Pediatric cardiology · 2023Pooled it
- Conductive hydrogel bioelectronics for chronic neuromodulation: From biomimetic design and bioactive interfaces to integrated neural platforms.Materials today. Bio · 2026Article
- Soft robotic devices for cardiovascular medicine.Nature reviews. Cardiology · 2026Review
- Magnetically gated millimeter-scale capsule power system for leadless electrotherapy.Science advances · 2026Article
- A Beginner's Guide to Cardiac Optical Mapping.Cardiovascular engineering and technology · 2026Review
- Minimally invasive bioelectronic implants.Nature materials · 2026Review
- Bioresorbable and optically readable triboelectric implants enabled by nanoscale iridophosphors.Nature nanotechnology · 2026Article
- Self-sustaining leadless intracardiac pacemaker powered by triboelectric nanogenerator.Science advances · 2026Article
- Clinical translation and engineering challenges of soft robotic cardiac sleeves for heart failure.Nature communications · 2026Review
- 3D-printed implantable bioelectronics enabled by anti-swelling and biphasic conductive hydrogels.Nature materials · 2026Article
- Strategies of Designing High-Efficiency Electrolyte Additives for Aqueous Magnesium Batteries: A Review.Nano-micro letters · 2026Review
- Ultra-flexible optoelectronic stimulator converts tissue-attenuated weak light into electrical signals for cardiac remodeling.Nature communications · 2026Article
- Flexible biodegradable wireless battery-free integrated theranostic adhesive patch.Bioactive materials · 2026Article
- Wearable Sensing for Clinical Physiology Monitoring: Emerging Paradigms.Physiology (Bethesda, Md.) · 2026Review
- Design, Implantation, and Biodistribution Study of a Resorbable Epidural Electrode Array Embedding Bioresorbable Polymeric Conductive Ink.ACS applied materials & interfaces · 2026Article
- Thermally Degradable Biocompatible Hydrogel as Transient Encapsulation Coating for Implantable Sensors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Transforming healthcare through in-body bioelectronic systems.Nature communications · 2026Review
- Analysis and prediction of cardiovascular research hotspots, trends and interdisciplinarity.Heart (British Cardiac Society) · 2026Article
- Soft, Flexible, and Stretchable Platforms for Tissue-Interfaced Bioelectronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Dissolution Study of Biodegradable Magnesium Silicide Thin Films for Transient Electronic Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
64 more citing papers are in PubMed but not listed here.
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Authors and funding
35 authors.
Funding
Abstract
Temporary cardiac pacemakers used in periods of need during surgical recovery involve percutaneous leads and externalized hardware that carry risks of infection, constrain patient mobility and may damage the heart during lead removal. Here we report a leadless, battery-free, fully implantable cardiac pacemaker for postoperative control of cardiac rate and rhythm that undergoes complete dissolution and clearance by natural biological processes after a defined operating timeframe. We show that these devices provide effective pacing of hearts of various sizes in mouse, rat, rabbit, canine and human cardiac models, with tailored geometries and operation timescales, powered by wireless energy transfer. This approach overcomes key disadvantages of traditional temporary pacing devices and may serve as the basis for the next generation of postoperative temporary pacing technology.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.