Evidence map›Paper›PMID 34183782›Full record

ArticleCell death and differentiation2021

Ki-67 gene expression.

Sigrid Uxa, Paola Castillo-Binder, Robin Kohler, Konstanze Stangner, Gerd A Müller, Kurt Engeland

Open access · hybridAbstract read
In one paragraph

Article in Cell death and differentiation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 207 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
207citing papers in PubMed, 1 pooled it
14.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

207 citing papers in PubMed, 1 synthesis or guideline pooled it, 278 citations in OpenAlex.

  1. Pooled it
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  20. Therapeutic Effects ofLife (Basel, Switzerland) · 2026
    Article

147 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Sigrid Uxa *Molecular Oncology, Medical School, University of Leipzig, Leipzig, Germany.ORCID http://orcid.org/0000-0002-8183-2153
Paola Castillo-Binder *Molecular Oncology, Medical School, University of Leipzig, Leipzig, Germany.
Robin KohlerMolecular Oncology, Medical School, University of Leipzig, Leipzig, Germany.
Konstanze StangnerMolecular Oncology, Medical School, University of Leipzig, Leipzig, Germany.
Gerd A MüllerMolecular Oncology, Medical School, University of Leipzig, Leipzig, Germany.ORCID http://orcid.org/0000-0002-4967-2487
Kurt EngelandMolecular Oncology, Medical School, University of Leipzig, Leipzig, Germany. engeland@medizin.uni-leipzig.de.ORCID http://orcid.org/0000-0003-3525-0440
Leipzig University · DELudwig-Maximilians-Universität München · DEUniversity Hospital Leipzig · DEUniversity of California, Santa Cruz · US

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) 424870812
6 · The paper itself

Abstract

Ki-67 serves as a prominent cancer marker. We describe how expression of the MKI67 gene coding for Ki-67 is controlled during the cell cycle. MKI67 mRNA and Ki-67 protein are maximally expressed in G

Indexed as

Biomarkers, TumorGene Expression Regulation, NeoplasticHumansKi-67 AntigenTransfectionBiomarkers, TumorKi-67 Antigen

Identifiers

PMID34183782
PMCPMC8629999
OpenAlexW3177364614

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.