Evidence map›Paper›PMID 34183412›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

The circadian clock gates

Brandon Mark, Liliana Bustos-González, Guadalupe Cascallares, Felipe Conejera, John Ewer

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
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  9. Review
  10. Timed receptor tyrosine kinase signaling couples the central and a peripheral circadian clock inProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Frontiers in physiology · 2022
    Article
  17. Natural alleles of the clock geneFrontiers in physiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Brandon MarkCentro Interdisciplinario de Neurociencias de Valparaíso, Universidad de Valparaíso, 2360102 Valparaíso, Chile.ORCID 0000-0002-2607-3756
Liliana Bustos-GonzálezCentro Interdisciplinario de Neurociencias de Valparaíso, Universidad de Valparaíso, 2360102 Valparaíso, Chile.ORCID 0000-0003-4825-7756
Guadalupe CascallaresCentro Interdisciplinario de Neurociencias de Valparaíso, Universidad de Valparaíso, 2360102 Valparaíso, Chile.ORCID 0000-0003-3459-9560
Felipe ConejeraCentro Interdisciplinario de Neurociencias de Valparaíso, Universidad de Valparaíso, 2360102 Valparaíso, Chile.
John EwerCentro Interdisciplinario de Neurociencias de Valparaíso, Universidad de Valparaíso, 2360102 Valparaíso, Chile; john.ewer@uv.cl.ORCID 0000-0002-6806-3628
University of Valparaíso · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The daily rhythm of adult emergence of holometabolous insects is one of the first circadian rhythms to be studied. In these insects, the circadian clock imposes a daily pattern of emergence by allowing or stimulating eclosion during certain windows of time and inhibiting emergence during others, a process that has been described as "gating." Although the circadian rhythm of insect emergence provided many of the key concepts of chronobiology, little progress has been made in understanding the bases of the gating process itself, although the term "gating" suggests that it is separate from the developmental process of metamorphosis. Here, we follow the progression through the final stages of

Indexed as

AgingAnimalsCircadian ClocksDrosophila melanogasterEcdysoneMetamorphosis, BiologicalModels, BiologicalMoltingReceptors, SteroidSignal TransductionTime FactorsWings, AnimalEcdysoneecdysone receptorReceptors, Steroidadult ecdysisecdysone actioneclosioninsect emergencemetamorphosis

Identifiers

PMID34183412
PMCPMC8271606
OpenAlexW3174454068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.