Evidence map›Paper›PMID 34182991›Full record

ArticleBMC health services research2021

Changes in the management of urinary tract infections in women: impact of the new recommendations on antibiotic prescribing behavior in France, between 2014 and 2019.

Arthur Piraux, Sébastien Faure, Kurt G Naber, Jakhongir F Alidjanov, Aline Ramond-Roquin

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC health services research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05847036 (Profiles of Urinary Tract Infections in General Practice), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05847036 unknown statusnot on this mapstarted 2023, after this paper: background citation

Profiles of Urinary Tract Infections in General Practice : a Prospective Multicentre Cohort Study

TypeobservationalSponsorCNGE ConseilRan2023 to 2025Enrolled500ConditionsUrinary Tract Infections
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Rising antimicrobial resistance in urinary tract infections in Türkiye: an urgent need for update on regional treatment strategies and for enhanced antimicrobial stewardship efforts.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  2. Article
  3. Rapid diagnosis of urinary tract infection with miniaturised point-of-care cultivation on a dipstick.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Arthur PirauxUniv Angers, Inserm, CNRS, MINT, SFR ICAT, 16 boulevard Daviers, F-49000, Angers, France. arthur.piraux@univ-angers.fr.
Sébastien FaureUniv Angers, Inserm, CNRS, MINT, SFR ICAT, 16 boulevard Daviers, F-49000, Angers, France.
Kurt G NaberDepartment of Urology, Technical University of Munich, Munich, Germany.
Jakhongir F AlidjanovDepartment of Urology, Pediatric Urology and Andrology, Justus-Liebig University of Giessen, Giessen, Germany.
Aline Ramond-RoquinFaculté de Santé, Département de Médecine Générale, Univ Angers, F-49000, Angers, France.
Inserm · FRTechnical University of Munich · DEUniversité d'Angers · FRUniversity of Giessen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUrinary tract infections (UTIs) are among the most common infections that require antibiotic therapy. In December 2015, new guidelines for UTI management were published in France with the aim of reducing antibiotic misuse and the risk of antimicrobial resistance.

objectivesTo analyze changes in antibiotic prescribing behavior for acute uncomplicated UTI in women in France from 2014 to 2019.

methodsRetrospective study using data extracted from the medico-administrative database 'OpenMedic' that is linked to the French National Health Data System and collects data on the reimbursement of prescribed drugs. The analyses focused on the number of boxes of antibiotics delivered by community pharmacies, the molecule class, and the prescriber's specialty.

resultsOverall, antibiotic dispensing by community pharmacies increased by 2% between 2014 and 2019, but with differences in function of the antibiotic class. The use of antibiotics recommended as first-line and second-line treatment increased (+ 41% for fosfomycin and + 7430% for pivmecillinam). Conversely, the dispensing of lomefloxacin and norfloxacin decreased by 80%, and that of ciprofloxacin by 26%. Some antibiotics were mostly prescribed by general practitioners (lomefloxacin, pivmecillinam) and others by secondary care physicians (ofloxacin). Dispensing increased for antibiotics prescribed by secondary care physicians (+ 13% between 2014 and 2019) and decreased for antibiotics prescribed by GPs (- 2% for the same period).

conclusionThese data suggest that the new recommendations are followed, as indicated by the increased prescription of fosfomycin and pivmecillinam and decreased prescription of fluoroquinolones. However, the efficient transmission and implementation of new recommendations by practitioners requires time, means and dedicated tools.

Indexed as

General PractitionersUrinary Tract InfectionsAnti-Bacterial AgentsFemaleFranceHumansPractice Patterns, Physicians'Retrospective StudiesAnti-Bacterial AgentsAntibiotic consumptionAntibiotic resistanceAntimicrobial resistanceEducational interventionGuideline adherencePrescriber-pharmacist collaborationUrinary tract infection

Identifiers

PMID34182991
PMCPMC8240268
OpenAlexW3129490298

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.