Evidence map›Paper›PMID 34182950›Full record

ArticleBMC pregnancy and childbirth2021

Iodine monitoring models contribute to avoid adverse birth outcomes related more than adequate iodine intake.

Jinju Dong, Shouyan Liu, Lingyun Wang, Xingjian Zhou, Qinghong Zhou, Congli Liu, Jingrui Zhu, Weilan Yuan, Wang-Yang Xu, Jie Deng

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pregnancy and childbirth, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jinju Dong *Department of Gynaecology and Obstetrics, Xiangyang No.1 People's Hospital, Hubei University of Medcine, Xiangyang, 441000, China.
Shouyan Liu *Department of Obstetrics, Pingdingshan No.1 People's Hospital, Pingdingshan, 467000, China.
Lingyun WangBiotecan Medical Diagnostics Co., Ltd, Zhangjiang Center for Translational Medicine, Shanghai, 201204, China.
Xingjian ZhouDepartment of Gynaecology and Obstetrics, Xiangyang No.1 People's Hospital, Hubei University of Medcine, Xiangyang, 441000, China.
Qinghong ZhouDepartment of Gynaecology and Obstetrics, Xiangyang No.1 People's Hospital, Hubei University of Medcine, Xiangyang, 441000, China.
Congli LiuDepartment of Gynaecology and Obstetrics, Xiangyang No.1 People's Hospital, Hubei University of Medcine, Xiangyang, 441000, China.
Jingrui ZhuDepartment of Obstetrics, Pingdingshan No.1 People's Hospital, Pingdingshan, 467000, China.
Weilan YuanBiotecan Medical Diagnostics Co., Ltd, Zhangjiang Center for Translational Medicine, Shanghai, 201204, China.
Wang-Yang XuSinglera Genomics (Shanghai) Ltd, Shanghai, 201318, China. Rita_xwy@126.com.
Jie DengDepartment of Gynaecology and Obstetrics, Xiangyang No.1 People's Hospital, Hubei University of Medcine, Xiangyang, 441000, China. gelanxiu123@163.com.
Hubei University · CNPingdingshan University · CNSinotech Genomics (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIodine plays an important role in pregnancy. How to maintain adequate iodine intake amongst pregnant women in each trimester of pregnancy to prevent adverse birth outcomes in central China is a challenge for clinical practice.

methods870 pregnant women and their infants were enrolled in the study. Urinary iodine concentration (UIC) was measured using an inductively coupled plasma mass spectrometry (ICP-MS). Maternal and newborn information were obtained during follow-up. Multinomial logistic regression models were established.

resultsMedian UIC of pregnant women was 172 ± 135 μg/L which is currently considered to be sufficient. Multivitamin supplements containing iodine, iodized salt intake and frequent milk intake were significantly associated with higher UIC. Multivariate logistic regression analysis showed that multivitamin supplements containing iodine and milk consumption were risk factors for more than adequate iodine (UIC ≥ 250 μg/L). Iodine-rich diet was significantly related to heavier birthweight, larger head circumference and longer femur length of the newborns while more than adequate iodine intake (UIC ≥ 250 μg/L) was a risk factor for macrosomia. Logistic regression models based on potential risk factors involving iodine containing supplements and iodine-rich diet were established to predict and screen pregnant women with high risk of more than adequate iodine intake among local pregnant women in different trimesters and guide them to supplement iodine reasonably to prevent the risk.

conclusionsMultivitamin supplements containing iodine and milk consumption were risk factors for maternal UIC ≥ 250 μg/L which was a risk factor for macrosomia. Iodine monitoring models were established to provide guidance for pregnant women to reduce the risk of more than adequate iodine intake, thereby contributing to reduce the risk of having a macrosomia.

Indexed as

Models, TheoreticalNutrition AssessmentAdultAnimalsChinaDietDietary SupplementsDiet SurveysEatingFemaleFetal MacrosomiaHumansInfant, NewbornIodineLogistic ModelsMilkIodineiodized saltSodium Chloride, DietaryMacrosomiaMonitoring modelMore than adequate iodine

Identifiers

PMID34182950
PMCPMC8240367
OpenAlexW3174043402

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.