Evidence map›Paper›PMID 34182492›Full record

ArticleIn vivo (Athens, Greece)

Ureteric Bud-derivatives in Wilms Tumor and Nephrogenic Rest.

Beatrix Sarkany, Gyula Kovacs, Daniel Banyai

Open access · diamondAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Beatrix SarkanyDepartment of Urology, Medical School, University of Pecs, Pecs, Hungary.
Gyula KovacsDepartment of Urology, Medical School, University of Pecs, Pecs, Hungary.
Daniel BanyaiDepartment of Urology, Medical School, University of Pecs, Pecs, Hungary; banyai.daniel@pte.hu.
University of Pecs · HUHeidelberg University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimRecent studies suggest that not only the nephrogenic blastema but also the ureteric bud is involved in oncogenesis of Wilms' tumor (WT). However, the occurrence of ureteric bud (UB) derivatives in nephrogenic rest is not yet known. The aim of our study was to find UB derivatives in WT. MATERIALS AND

methodsKeratin 17 (KRT17) is expressed exclusively in UB in foetal kidneys. In this study KRT17 immunohistochemistry was used to detect UB-derivatives in 21 triphasic, 2 stromal and 3 epithelial predominant WTs and 9 nephrogenic rests.

resultsWe have detected KRT17 positive tubular structures resembling UB in 3 of 9 nephrogenic rests and 15 of 26 WTs.

conclusionNot only the metanephric blastema but also the UB is involved in the histogenesis of nephrogenic rest and WT.

Indexed as

Kidney NeoplasmsWilms TumorCell Transformation, NeoplasticHumansImmunohistochemistryKidneyimmunohistochemistrykeratin 17nephrogenic restUreteric budWilms’tumor

Identifiers

PMID34182492
PMCPMC8286514
OpenAlexW3173973402

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.