ReviewNeurobiology of aging2021
Brain activity during walking in older adults: Implications for compensatory versus dysfunctional accounts.
Review in Neurobiology of aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 27 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Changes of Plantar Pressure and Electroencephalographic Signals During Pedal Walking and Vision-deprivation Walking in Stroke Patients.
Neural Mechanism Changes in Stroke Patients During Challenging Environments
The Effectiveness of Whole Body Vibration Training in Improving Brain Activity, Bone Mineral Density, Quality of Life, and Biomarkers for the Older People With Dynapenic Abdominal Obesity
Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- The impact of walking training on cognitive function in older adults: a meta-analysis.Frontiers in psychology · 2026Pooled it
- Verbal fluency dual-tasks show greater age-related cognitive-motor interference: a meta-analysis of walking performance.Experimental brain research · 2025Pooled it
- Dose-response relationship of physical exercise interventions for balance performance in children and adolescents with intellectual disabilities: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Synergistic effects of exercise, cognitive training and vitamin D on gait performance and falls in mild cognitive impairment-secondary outcomes from the SYNERGIC trial.Age and ageing · 2025Trial
- Factors associated with the risk of falls and their relationship with cognitive function in older adults with cognitive impairment: a cross-sectional study.GeroScience · 2026Article
- Cortical activation, gait performance, and muscle activation during dual-task walking in older adults with mild cognitive impairment.BMC geriatrics · 2026Article
- Brain adaptations in challenging walking task of people with stroke: an experimental study.Journal of neuroengineering and rehabilitation · 2026Article
- Cognitive Impairment Is Associated with Disrupted Motor Planning in Older Adults.Neuro-degenerative diseases · 2026Article
- Link of gray matter volume to cognitive and motor function in elderly patients with mild cognitive impairment.World journal of psychiatry · 2025Article
- Correlates of gait speed changes during uneven terrain walking in older adults: differential roles of cognitive and sensorimotor function.Experimental brain research · 2025Article
- Article
- Associations between declines in uneven terrain walking speed and visuospatial working memory in older adults.Frontiers in aging neuroscience · 2025Article
- Disability Moderates Dual Task Walking Performance and Neural Efficiency in Older Adults With Multiple Sclerosis.Neurorehabilitation and neural repair · 2024Article
- Reduced Proactive and Reactive Cognitive Flexibility in Older Adults Underlies Performance Costs During Dual-Task Walking: A Mobile Brain/Body Imaging (MoBI) Study.bioRxiv : the preprint server for biology · 2024Article
- Positron emission tomography neuroimaging of [Frontiers in neuroscience · 2024Article
- Electrical brain activity during human walking with parametric variations in terrain unevenness and walking speed.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Examining the influence of self-care practices on brain activity in healthy older adults.Frontiers in aging neuroscience · 2024Article
- Prefrontal cortical activity during uneven terrain walking in younger and older adults.Frontiers in aging neuroscience · 2024Article
- Novel automaticity index reveals a cognitive ability-related decline in gait automaticity during dual-task walking.bioRxiv : the preprint server for biology · 2023Article
- Neural correlates of gait adaptation in younger and older adults.Scientific reports · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
A prominent trend in the functional brain imaging literature is that older adults exhibit increased brain activity compared to young adults to perform a given task. This phenomenon has been extensively studied for cognitive tasks, with the field converging on interpretations described in two alternative accounts. One account interprets over-activation in older adults as reflecting neural dysfunction (increased brain activity - indicates poorer performance), whereas another interprets it as neural compensation (increased brain activity - supports better performance). Here we review studies that have recorded brain activity and walking measurements in older adults, and we categorize their findings as reflecting either neural dysfunction or neural compensation. Based on this synthesis, we recommend including multiple task difficulty levels in future work to help differentiate if and when compensation fails as the locomotion task becomes more difficult. Using multiple task difficulty levels with neuroimaging will lead to a more advanced understanding of how age-related changes in locomotor brain activity fit with existing accounts of brain aging and support the development of targeted neural rehabilitation techniques.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.