Evidence map›Paper›PMID 34182069›Full record

ReviewAmerican journal of infection control2022

Review of aerosolized hydrogen peroxide, vaporized hydrogen peroxide, and hydrogen peroxide gas plasma in the decontamination of filtering facepiece respirators.

Daniel Berger, Gabrielle Gundermann, Anjana Sinha, Morgan Moroi, Neerav Goyal, Anthony Tsai

Open access · bronzeAbstract readReview
In one paragraph

Review in American journal of infection control, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Daniel BergerPenn State College of Medicine, Hershey, PA.
Gabrielle GundermannPenn State College of Medicine, Hershey, PA.
Anjana SinhaPenn State College of Medicine, Hershey, PA.
Morgan MoroiPenn State College of Medicine, Hershey, PA; Division of Cardiac, Thoracic, and Vascular Surgery, Department of Surgery, New York-Presbyterian Hospital/Columbia University Medical Center, New York, NY.
Neerav GoyalPenn State College of Medicine, Hershey, PA.
Anthony TsaiPenn State College of Medicine, Hershey, PA. Electronic address: atsai1@pennstatehealth.psu.edu.
Penn State Milton S. Hershey Medical Center · USNewYork–Presbyterian Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to over 170?million cases worldwide with over 33.2?million cases and 594,000 deaths in the US alone as of May 31st, 2021. The pandemic has also created severe shortages of personal protective equipment, particularly of filtering facepiece respirators (FFRs). The Centers for Disease Control and Prevention (CDC) has issued recommendations to help conserve FFRs, as well as crisis standards, including four criteria required for decontamination of the traditionally single use respirators. This review is designed to provide an overview of the current literature on vaporized hydrogen peroxide (vHP), hydrogen peroxide gas plasma (HPGP), and aerosolized hydrogen peroxide (aHP) with respect to each of the four CDC decontamination criteria.

methodsPubMed and Medrxiv were queried for relevant articles. All articles underwent a title and abstract screen as well as subsequent full text screen by two blinded reviewers if indicated.

resultsSearches yielded 195 papers, of which, 79 were found to be relevant. Of those, 23 papers presented unique findings and 8 additional articles and technical papers were added to provide a comprehensive review. Overall, while there are potential concerns for all 3 decontamination methods, we found that vHP has the most evidence supporting its use in FFR decontamination consistent with CDC recommendation.

conclusionsFuture research is recommended to evaluate biological inactivation and real world fit failures after FFR reuse.

Indexed as

COVID-19Hydrogen PeroxideDecontaminationEquipment ReuseHumansSARS-CoV-2Ventilators, MechanicalHydrogen PeroxideAerosolized Hydrogen PeroxideCOVID-19DecontaminationFiltering Facepiece RespiratorN95 RespiratorVaporized Hydrogen Peroxide

Identifiers

PMID34182069
PMCPMC8233052
OpenAlexW3176762932

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.