Evidence map›Paper›PMID 34181919›Full record

ArticleEnvironmental research2021

Parkinson's disease aggravation in association with fine particle components in New York State.

Yanelli Nunez, Amelia K Boehme, Maggie Li, Jeff Goldsmith, Marc G Weisskopf, Diane B Re, Ana Navas-Acien, Aaron van Donkelaar, Randall V Martin, Marianthi-Anna Kioumourtzoglou

Open access · greenAbstract read
In one paragraph

Article in Environmental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. PMiScience · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Review
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  8. Review
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  15. Article
  16. PMEnvironmental epidemiology (Philadelphia, Pa.) · 2022
    Article
  17. Review
  18. Long-term exposure to PMEnvironment international · 2022
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Yanelli NunezDepartment of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, NY, USA. Electronic address: yn2295@cumc.columbia.edu.
Amelia K BoehmeDepartment of Epidemiology and Neurology, Columbia University, New York, NY, USA.
Maggie LiDepartment of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, NY, USA.
Jeff GoldsmithDepartment of Biostatistics, Columbia University Mailman School of Public Health, New York, NY, USA.
Marc G WeisskopfDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Diane B ReDepartment of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, NY, USA.
Ana Navas-AcienDepartment of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, NY, USA.
Aaron van DonkelaarDepartment of Energy, Environmental & Chemical Engineering, Washington University at St. Louis, MO, USA; Department of Physics and Atmospheric Science, Dalhousie University, Halix, Nova Scotia, Canada.
Randall V MartinDepartment of Energy, Environmental & Chemical Engineering, Washington University at St. Louis, MO, USA; Department of Physics and Atmospheric Science, Dalhousie University, Halix, Nova Scotia, Canada.
Marianthi-Anna KioumourtzoglouDepartment of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, NY, USA.
Columbia University · USDalhousie University · CAHarvard University · USWashington University in St. Louis · US

Funding

True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7M
Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI JAIME ELIZABETH HART · 1985 to 2026
$44.6M
Supplemental Training in Making Data FAIR and AI/ML ReadyT32ES007322 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Pam R Factor-Litvak, Allison Kupsco · 2000 to 2026
$12.1M
GRADUATE TRAINING IN BIOSTATISTICST32ES007142 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI Brent Andrew Coull · 1985 to 2026
$11.9M
National Cohort Studies of Alzheimer's Disease, Related Dementias and Air PollutionR01AG066793 · NIA · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI ZANOBETTI, ANTONELLA · 2020 to 2025
$4.2M
(R01 Transfer) Characterizing the link between multiple environmental exposures and Parkinsons disease exacerbationR01ES034373 · NIEHS · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Danielle Braun, Antonella Zanobetti · 2022 to 2026
$2.9M
Principal Component Pursuit to Assess Exposure to Environmental Mixtures in Epidemiologic StudiesR01ES028805 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KIOUMOURTZOGLOU, MARIANTHI-ANNA · 2018 to 2021
$2.2M
Air Pollution Exposure and Risk of Amyotrophic Lateral Sclerosis (ALS)R21ES028472 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KIOUMOURTZOGLOU, MARIANTHI-ANNA · 2018 to 2019
$406k
NIA NIH HHS R01 AG066793NIEHS NIH HHS P30 ES000002NIEHS NIH HHS P30 ES009089NIEHS NIH HHS R01 ES028805NIEHS NIH HHS R01 ES034373NIEHS NIH HHS R21 ES028472NIEHS NIH HHS T32 ES007142NIEHS NIH HHS T32 ES007322
6 · The paper itself

Abstract

backgroundLong-term exposure to fine particulate matter (PM

objectiveTo characterize the association between specific PM

methodsWe obtained data on hospitalizations from the New York Department of Health Statewide Planning and Research Cooperative System (2000-2014) to calculate annual first PD hospitalization counts in New York State per county. We used well-validated prediction models at 1 km

resultsWe observed a total of 197,545 PD first hospitalizations in NYS from 2000 to 2014. The annual average count per county was 212 first hospitalizations. The RR (95% confidence interval) for PD aggravation was 1.06 (1.03, 1.10) per one standard deviation (SD) increase in nitrate concentrations and 1.06 (1.04, 1.09) for the corresponding increase in OM concentrations. We also found a nonlinear inverse association between PD aggravation and BC at concentrations above the 96th percentile. We found a marginal association with SS and no association with sulfate or soil exposure.

conclusionIn this study, we detected associations between the PM

Indexed as

Air PollutionParkinson DiseaseHumansNew YorkParticulate MatterParticulate MatterAir pollutionEpidemiologyLong-term exposuresNeurodegenerative diseasesParkinson's diseasePM2.5 chemical composition

Identifiers

PMID34181919
PMCPMC8478789
OpenAlexW3174220639

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.