ArticleRevista de la Facultad de Ciencias Medicas (Cordoba, Argentina)2021
Stable Chronic Obstructive Pulmonary Disease Associated With Cognitive Impairment: Possible Causality Factor
Article in Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Progress of Research on Cognitive Impairment in Patients With Chronic Obstructive Pulmonary Disease.Actas espanolas de psiquiatria · 2026Review
- The influence of physical fatigue on telephone-based neuropsychological test performance in COVID-19 survivors.European archives of psychiatry and clinical neuroscience · 2025Article
- [Cognitive alterations in patients recovered from COVID-19 treated in Cardiopulmonary Rehabilitation].Revista medica del Instituto Mexicano del Seguro Social · 2023Observational
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Authors and funding
6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgruoundChronic Obstructive Pulmonary Disease (COPD), a preventable and underdiagnosed pathology, can be defined as a progressive and poorly reversible limitation to airflow as a result of a persistent inflammatory response due to inhalation of harmful substances, particularly tobacco smoke. The disease has a systemic impact. Among other conditions, it may increase the risk of cognitive impairment along with its associated consequences.
methodsProspective, cross-sectional, observational and analytical design. The space were COPD patients who visited in two health institutions from June 2017 to September 2018. Non-probabilistic and convenience sampling. Data were collected on demographics, tobacco consumption, comorbidities (Charlson index), a validated scale for dyspnea (MCRm), the main symptom in COPD and the COPD Assessment Test (CAT) were applied along with a history of exacerbation of the disease. The severity of COPD was evaluated by spirometry according to GOLD guideline. Cognitive impairment was assessed using Neuropsi. OUTCOMES: The final sample consisted of 44 subjects. According to spirometry and GOLD, 7 patients (15.9%) classified in group 1 (mild), 19 (43.2%) in group 2 (moderate), 11 (25%) in group 3 (severe) and 7 (15.9%) in group 4 (very serious). Of the 44 patients recruited, 28 (63.6%) had normal cognitive function and 16 (36.3%) had some degree of cognitive impairment. Memory was the most compromised function.
conclusionDifficulties in recruitment impeded reaching the expected sample size. However, a trend was observed favoring the association. It is important to insist on avoiding smoking because it seems to increase the risk of cognitive impairment that further disrupts the quality of life and makes treatment difficult.
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