ArticlePLoS genetics2021
VAL genes regulate vegetative phase change via miR156-dependent and independent mechanisms.
Article in PLoS genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 32 citations in OpenAlex.
- TheProceedings of the National Academy of Sciences of the United States of America · 2026Article
- The transcriptional regulator VAL1 promotes Arabidopsis flowering by repressing the organ boundary genes BOP1 and BOP2.Plant physiology · 2025Article
- SPL13 controls a root apical meristem phase change by triggering oriented cell divisions.Science (New York, N.Y.) · 2024Article
- Temporal regulation of vegetative phase change in plants.Developmental cell · 2024Review
- Short-interval traffic lines: versatile tools for genetic analysis in Arabidopsis thaliana.G3 (Bethesda, Md.) · 2022Article
- Article
- PICKLE associates with histone deacetylase 9 to mediate vegetative phase change in Arabidopsis.The New phytologist · 2022Article
- Interaction Analysis between theInternational journal of molecular sciences · 2022Article
- Review
- microRNAs and Their Roles in Plant Development.Frontiers in plant science · 2022Review
- Convergent evolution of the annual life history syndrome from perennial ancestors.Frontiers in plant science · 2022Review
- Effects of the vegetative propagation method on juvenility inForestry research · 2022Article
- Cell division in the shoot apical meristem is a trigger for miR156 decline and vegetative phase transition inProceedings of the National Academy of Sciences of the United States of America · 2021Article
- The Regulation of Plant Vegetative Phase Transition and Rejuvenation: miRNAs, a Key Regulator.Epigenomes · 2021Review
- Post-Embryonic Phase Transitions Mediated by Polycomb Repressive Complexes in Plants.International journal of molecular sciences · 2021Review
- Reprogramming of Histone H3 Lysine Methylation During Plant Sexual Reproduction.Frontiers in plant science · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
How organisms control when to transition between different stages of development is a key question in biology. In plants, epigenetic silencing by Polycomb repressive complex 1 (PRC1) and PRC2 plays a crucial role in promoting developmental transitions, including from juvenile-to-adult phases of vegetative growth. PRC1/2 are known to repress the master regulator of vegetative phase change, miR156, leading to the transition to adult growth, but how this process is regulated temporally is unknown. Here we investigate whether transcription factors in the VIVIPAROUS/ABI3-LIKE (VAL) gene family provide the temporal signal for the epigenetic repression of miR156. Exploiting a novel val1 allele, we found that VAL1 and VAL2 redundantly regulate vegetative phase change by controlling the overall level, rather than temporal dynamics, of miR156 expression. Furthermore, we discovered that VAL1 and VAL2 also act independently of miR156 to control this important developmental transition. In combination, our results highlight the complexity of temporal regulation in plants.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.