ArticleAndrologia2021
COVID-19 vaccine hesitancy linked to increased internet search queries for side effects on fertility potential in the initial rollout phase following Emergency Use Authorization.
Article in Andrologia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed, 4 syntheses or guidelines pooled it, 95 citations in OpenAlex.
- Acceptance-Hesitancy of COVID-19 Vaccination and Factors Affecting It in Adults: Systematic Review Study.Immunity, inflammation and disease · 2024Pooled it
- Effect of female coronavirus disease 2019 vaccination on assisted reproductive outcomes: a systematic review and meta-analysis.Fertility and sterility · 2023Pooled it
- Effect of COVID-19 vaccination on semen parameters: A systematic review and meta-analysis.Journal of medical virology · 2023Pooled it
- Pooled it
- Perspectives on COVID-19 vaccine decision-making in women of reproductive age: A social approach.Patient education and counseling · 2026Article
- Evaluation of Google search trends for COVID-19 vaccination administration efforts within an urban department of public health.Journal of public health research · 2026Article
- The effect of Covid-19 vaccines on semen parameters of patients undergoing infertility investigations: a self-controlled before-and-after study.Scientific reports · 2026Article
- Grocery store workers' knowledge, attitudes, and barriers influencing uptake of COVID-19 vaccine in the United States: a qualitative study.BMC public health · 2026Article
- The influence of SARS-CoV-2 vaccination on in vitro fertilization outcomes.Human vaccines & immunotherapeutics · 2025Article
- The complex landscape of vaccine hesitancy and hesitant adopters: Quantitative predictors and thematic insights into COVID-19 vaccine attitudes.Human vaccines & immunotherapeutics · 2025Article
- The Role of Influencers and Echo Chambers in the Diffusion of Vaccine Misinformation: Opinion Mining in a Taiwanese Online Community.JMIR infodemiology · 2025Article
- Harnessing Internet Search Data as a Potential Tool for Medical Diagnosis: Literature Review.JMIR mental health · 2025Review
- Decline in and recovery of fertility rates after COVID-19-related state of emergency in Japan.BMJ open · 2024Article
- Measuring vaccination coverage and concerns of vaccine holdouts from web search logs.Nature communications · 2024Article
- Analyzing Google COVID-19 Vaccine Intent Search Trends and Vaccine Readiness in the United States: Panel Data Study.Online journal of public health informatics · 2024Article
- Fertility outcomes in women undergoing Assisted Reproductive Treatments after COVID-19 vaccination: A prospective cohort study.International journal of fertility & sterility · 2024Article
- SARS-CoV-2 Vaccination is Not Associated With Involuntary Childlessness in Female Healthcare Workers: A Multicenter Cohort Study.Influenza and other respiratory viruses · 2024Article
- A Scoping Review on Gender/Sex Differences in COVID-19 Vaccine Intentions and Uptake in the United States.American journal of health promotion : AJHP · 2024Article
- Temporal trends in online searches related to COVID-19 vaccine safety: A digital infodemiology study.Health promotion perspectives · 2024Article
- COVID-19 vaccination up-take in three districts of Nepal.Human vaccines & immunotherapeutics · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Emergency Use Authorization (EUA) of the COVID-19 vaccine on December 11, 2020 has been met with hesitancy for uptake with some citing potential impacts on future fertility. We hypothesised that irrespective of sex, fertility-related queries would markedly increase during the 48 days following EUA of the coronavirus vaccine. We sought to objectively identify trends in internet search queries on public concerns regarding COVID-19 vaccine side effects on fertility that might impact vaccine uptake. We used Google Trends to investigate queries in Google's Search Engine relating to the coronavirus vaccine and fertility between 10/24/2020 and 1/27/2021. The five most queried terms were identified as: 'COVID Vaccine Fertility', 'COVID Vaccine and Infertility', 'COVID Vaccine Infertility', 'COVID Vaccine Fertility CDC', and 'COVID 19 Vaccine Infertility' with an increase of 710.47%, 207.56%, 264.35%, 2,943.7%, and 529.26%, respectively, all p < .001. This study indicates that there was an increase in online COVID-19 vaccine-related queries regarding fertility side effects coinciding with the Emergency Use Authorization (EUA) on December 11, 2020. Our results objectively evidence the increased concern regarding the vaccine and likely demonstrate a major cause for hesitancy in vaccine uptake. Future studies and counselling with patients should be undertaken to help mitigate these concerns.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.