ArticleJournal of urban health : bulletin of the New York Academy of Medicine2021
The Ontario Integrated Supervised Injection Services Cohort Study of People Who Inject Drugs in Toronto, Canada (OiSIS-Toronto): Cohort Profile.
Article in Journal of urban health : bulletin of the New York Academy of Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Recent hydromorphone injection and risk of incident infective endocarditis among people who inject drugs in Toronto, Canada: a cohort study.Harm reduction journal · 2026Article
- Economic and epidemiological burden of medical complications of unregulated drug use among people who inject drugs in Québec.Substance abuse treatment, prevention, and policy · 2026Article
- Complex trauma and perceived barriers to treatment among people accessing a supervised injecting facility.European journal of psychotraumatology · 2025Article
- The Effect of Opioid Agonist Treatment on Injection-Related Sequelae: A Population-Based Observational Study.Drug safety · 2025Observational
- Expanding supervised consumption services in rural Canada: Bridging gaps.Canadian journal of public health = Revue canadienne de sante publique · 2025Article
- A Preliminary Assessment of Short-Term Social and Substance Use-Related Outcomes Among Clients of Integrated Safer Opioid Supply Pilot Programs in Toronto, Canada.International journal of mental health and addiction · 2025Article
- An individual-based dynamic model to assess interventions to mitigate opioid overdose risk.Harm reduction journal · 2024Article
- Economic evaluation of the effect of needle and syringe programs on skin, soft tissue, and vascular infections in people who inject drugs: a microsimulation modelling approach.Harm reduction journal · 2024Article
- The impact of the COVID-19 pandemic on people who use drugs in three Canadian cities: a cross-sectional analysis.Harm reduction journal · 2024Article
- Rapid hepatitis C virus point-of-care RNA testing and treatment at an integrated supervised consumption service in Toronto, Canada: a prospective, observational cohort study.Lancet regional health. Americas · 2023Article
- Disease-related stigma among people who inject drugs in Toronto amidst the COVID-19 pandemic.Drug and alcohol dependence reports · 2023Article
- Evaluating interventions to facilitate opioid agonist treatment access among people who inject drugs in Toronto, Ontario during COVID-19 pandemic restrictions.The International journal on drug policy · 2022Article
- Service utilization patterns and characteristics among clients of integrated supervised consumption sites in Toronto, Canada.Harm reduction journal · 2022Article
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
The Ontario Integrated Supervised Injection Services cohort in Toronto, Canada (OiSIS-Toronto) is an open prospective cohort of people who inject drugs (PWID). OiSIS-Toronto was established to evaluate the impacts of supervised consumption services (SCS) integrated within three community health agencies on health status and service use. The cohort includes PWID who do and do not use SCS, recruited via self-referral, snowball sampling, and community/street outreach. From 5 November 2018 to 19 March 2020, we enrolled 701 eligible PWID aged 18+ who lived in Toronto. Participants complete interviewer-administered questionnaires at baseline and semi-annually thereafter and are asked to consent to linkages with provincial healthcare administrative databases (90.2% consented; of whom 82.4% were successfully linked) and SCS client databases. At baseline, 86.5% of participants (64.0% cisgender men, median ([IQR] age= 39 [33-49]) had used SCS in the previous 6 months, of whom most (69.7%) used SCS for <75% of their injections. A majority (56.8%) injected daily, and approximately half (48.0%) reported fentanyl as their most frequently injected drug. As of 23 April 2021, 291 (41.5%) participants had returned for follow-up. Administrative and self-report data are being used to (1) evaluate the impact of integrated SCS on healthcare use, uptake of community health agency services, and health outcomes; (2) identify barriers and facilitators to SCS use; and (3) identify potential enhancements to SCS delivery. Nested sub-studies include evaluation of "safer opioid supply" programs and impacts of COVID-19.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.