Evidence map›Paper›PMID 34181140›Full record

ArticleJournal of autism and developmental disorders2023

Newborn Auditory Brainstem Responses in Children with Developmental Disabilities.

Christine F Delgado, Elizabeth A Simpson, Guangyu Zeng, Rafael E Delgado, Oren Miron

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of autism and developmental disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Who, when, where, and why: A systematic review of "late diagnosis" in autism.Autism research : official journal of the International Society for Autism Research · 2025
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Infant sensory gating and a developmental cascade to autistic traits and anxiety.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Christine F DelgadoDepartment of Psychology, University of Miami, PO Box 248185, Coral Gables, FL, 33124-0721, USA. cdelgado@umiami.edu.ORCID http://orcid.org/0000-0001-8812-8831
Elizabeth A SimpsonDepartment of Psychology, University of Miami, PO Box 248185, Coral Gables, FL, 33124-0721, USA.
Guangyu ZengDepartment of Psychology, University of Miami, PO Box 248185, Coral Gables, FL, 33124-0721, USA.
Rafael E DelgadoBiomedical Engineering, University of Miami, Coral Gables, FL, USA.
Oren MironDepartment of Health Systems Management, Ben-Gurion University of the Negev, Beer Sheva, Israel.
University of Miami · USBen-Gurion University of the Negev · IL

Funding

Screening Device for Autism Spectrum Disorders using High Stimulation Rate ABR with Continuous Loop Averaging DeconvolutionR43DC018430 · NIDCD · INTELLIGENT HEARING SYSTEMS · PI DELGADO, RAFAEL E · 2019 to 2019
$200k
National Institutes of Health NIH SBIR 1R43DC018430-01National Science Foundation NSF CAREER Award 1653737NIDCD NIH HHS R43 DC018430NIH HHS NIH SBIR 1R43DC018430-01
6 · The paper itself

Abstract

We integrated data from a newborn hearing screening database and a preschool disability database to examine the relationship between newborn click evoked auditory brainstem responses (ABRs) and developmental disabilities. This sample included children with developmental delay (n = 2992), speech impairment (SI, n = 905), language impairment (n = 566), autism spectrum disorder (ASD, n = 370), and comparison children (n = 128,181). We compared the phase of the ABR waveform, a measure of sound processing latency, across groups. Children with SI and children with ASD had greater newborn ABR phase values than both the comparison group and the developmental delay group. Newborns later diagnosed with SI or ASD have slower neurological responses to auditory stimuli, suggesting sensory differences at birth.

Indexed as

Autism Spectrum DisorderLanguage DisordersAcoustic StimulationChildChild, PreschoolDevelopmental DisabilitiesEvoked Potentials, Auditory, Brain StemHumansInfant, NewbornSpeech DisordersAuditory brainstem responseAutism spectrum disorderDevelopmental disabilitiesEarly identificationSpeech impairment

Identifiers

PMID34181140
PMCPMC9549590
OpenAlexW3177044507

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.