Evidence map›Paper›PMID 34181111›Full record

ArticleJapanese journal of ophthalmology2021

Prevalence and incidence rates and treatment patterns of non-infectious uveitis in Japan: real-world data using a claims database.

Akihiko Umazume, Nobuyuki Ohguro, Annabelle A Okada, Kenichi Namba, Koh-Hei Sonoda, Hidekazu Tsuruga, Kazuo Morita, Hiroshi Goto

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Article in Japanese journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Akihiko UmazumeDepartment of Ophthalmology, Tokyo Medical University, Tokyo, Japan.
Nobuyuki OhguroJapan Community Healthcare Organization Osaka Hospital, Osaka, Japan.
Annabelle A OkadaDepartment of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan.
Kenichi NambaDepartment of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Koh-Hei SonodaDepartment of Clinical Medicine, Kyushu University Faculty of Medical Sciences, Fukuoka, Japan.
Hidekazu TsurugaAbbVie GK, 3-1-21 Shibaura, Minato-ku, Tokyo, 108-0023, Japan. hidekazu.tsuruga@abbvie.com.
Kazuo MoritaAbbVie GK, 3-1-21 Shibaura, Minato-ku, Tokyo, 108-0023, Japan.
Hiroshi GotoDepartment of Ophthalmology, Tokyo Medical University, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo estimate the nationwide, longitudinal prevalence and incidence rates and assess treatment patterns of non-infectious uveitis (NIU) in Japan. STUDY

designA retrospective study.

methodsHealth insurance claims' data of patients with NIU were extracted from the Japan Medical Data Center (JMDC) database and analyzed descriptively (data extraction period, January 2011 to May 2017). Behçet's disease (BD), Vogt-Koyanagi-Harada (VKH) disease, and sarcoidosis were selected as the primary diseases of NIU.

resultsFrom 2011 to 2016, the mean and median age of patients increased. Most (> 90%) patients were categorized as "undifferentiated NIU" (NIU without specific primary disease information after excluding BD-, VKH disease-, and sarcoidosis-associated NIU). Over 60% of patients with NIU were treated at non-hospital clinics, while the rest were treated at university, public, or other hospitals. The estimated prevalence rate of NIU was 386.5 per 100,000 persons (95% confidence interval [CI], 374.5-398.6) in 2011 and 439.3 per 100,000 persons (95% CI, 432.3-446.3) in 2016; the estimated incidence rate was 189.7 per 100,000 persons (95% CI, 181.2-198.5) in 2012 and 207.8 per 100,000 persons (95% CI, 202.2-213.5) in 2016. Most patients' prescribed uveitis drugs were ophthalmic drops over the first 6 months after patient presentation and entry into the JMDC database, followed by systemic corticosteroids.

conclusionThe estimated prevalence of NIU in Japan in recent years was approximately 400 with incidence of 200 per 100,000 persons.

Indexed as

UveitisHumansIncidenceJapanPrevalenceRetrospective StudiesClaims databaseEpidemiologyJapanNon-infectious uveitisTreatment pattern

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.