Evidence map›Paper›PMID 34180843›Full record

Trial reportAnnals of family medicine

Reducing Expectations for Antibiotics in Patients With Upper Respiratory Tract Infections: A Primary Care Randomized Controlled Trial.

Anna Ishani Perera, Mark Greenslade Thomas, Keith James Petrie, Janet Frater, Daniel Dang, Kiralee Ruth Schache, Amelia Frances Akroyd, Stephen Robert Ritchie

Open access · diamondAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Annals of family medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Bioscience of microbiota, food and health · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Post-consultation acute respiratory tract infection recovery: a latent class-informed analysis of individual patient data.The British journal of general practice : the journal of the Royal College of General Practitioners · 2023
    Article
  9. Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Anna Ishani PereraDepartment of Psychological Medicine, University of Auckland, Auckland, New Zealand anna.perera@auckland.ac.nz.
Mark Greenslade ThomasDepartment of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand.
Keith James PetrieDepartment of Psychological Medicine, University of Auckland, Auckland, New Zealand.
Janet FraterBalmoral Doctors, Auckland, New Zealand.
Daniel DangEastern Institute of Technology, Napier, New Zealand.
Kiralee Ruth SchacheDepartment of Psychological Medicine, University of Auckland, Auckland, New Zealand.
Amelia Frances AkroydDepartment of Psychological Medicine, University of Auckland, Auckland, New Zealand.
Stephen Robert RitchieDepartment of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand.
University of Auckland · NZEastern Institute of Technology · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMany family practitioners prescribe antibiotics for patients with upper respiratory tract infections (URTIs) to meet patients' expectations. We evaluated the impact of providing brief tablet-based information about antibiotic treatment of URTIs on patients' expectations for antibiotics and on family practitioners' antibiotic-prescribing behavior.

methodsWe performed a 3-arm randomized controlled trial among patients presenting with URTIs at 2 urban family practices in Auckland, New Zealand, during winter 2018. Participants were randomly allocated to view a presentation about the futility of antibiotic treatment of URTIs, the adverse effects associated with antibiotics, or the benefits of healthy diet and exercise (active control), immediately before their consultation. Before and after viewing the presentations, participants used a Likert scale to rate the strength of their belief that antibiotics are effective for treating URTIs and of their desire to be prescribed an antibiotic. Patients reported whether an antibiotic had been prescribed, and pharmacy dispensing records were reviewed to determine whether an antibiotic was dispensed.

resultsParticipants who viewed either the futility or the adverse effects presentation had greater reductions in their expectations to receive antibiotics than the control group. The mean reduction (95% CI) was 1.1 (0.8-1.3) for the futility group, 0.7 (0.4-0.9) for the adverse effects group, and 0.1 (0-0.3) for the control group (Cohen

conclusionsA brief tablet-based waiting room intervention significantly reduced participants' expectations about receiving antibiotics for URTI immediately before their family practitioner consultation. The intervention did not influence family practitioner prescribing behavior, however.

Indexed as

Anti-Bacterial AgentsRespiratory Tract InfectionsHumansMotivationNew ZealandPractice Patterns, Physicians'Primary Health CareAnti-Bacterial Agentsantibiotic prescriptionsantimicrobial stewardship educationfamily practicepatient expectationsphysician-patient communicationpractice-based researchprimary health carerespiratory tract infections

Identifiers

PMID34180843
PMCPMC8118493
OpenAlexW3162980550

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.