ArticleDeutsches Arzteblatt international2021
Incidence and Mortality of Proximal and Distal Colorectal Cancer in Germany—Trends in the Era of Screening Colonoscopy.
Article in Deutsches Arzteblatt international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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27 citing papers in PubMed, 42 citations in OpenAlex.
- Polyp detection in the cecum and ascending colon by dye based chromoendoscopy - Is its routine use justified?Revista do Colegio Brasileiro de Cirurgioes · 2023Trial
- Potential for enhancing efficacy of screening colonoscopy by lowering starting ages and extending screening intervals: A modelling study for Germany.International journal of cancer · 2025Article
- Clinical Features in Patients With Early-Onset Colorectal Cancer: An Evaluation of Data From the StuDoQ Database.Deutsches Arzteblatt international · 2025Article
- Is Colonoscopy Alone Adequate for Surveillance in Stage I Colorectal Cancer?Cancer research and treatment · 2025Article
- Trends in colorectal cancer cases at a Mexican secondary-care hospital.Ecancermedicalscience · 2025Article
- [Telemedicine and AI-supported diagnostics in the daily routine of visceral medicine].Chirurgie (Heidelberg, Germany) · 2025Article
- Proportion and characteristics of screen-detected and non-screen-detected colo-rectal cancers in Germany.Acta oncologica (Stockholm, Sweden) · 2024Article
- [Muscle pain in myositis in a young female patient: what is behind this?]Innere Medizin (Heidelberg, Germany) · 2024Article
- PolypNextLSTM: a lightweight and fast polyp video segmentation network using ConvNext and ConvLSTM.International journal of computer assisted radiology and surgery · 2024Article
- Intended and Actual Participation in the Colorectal Cancer Screening Program.Deutsches Arzteblatt international · 2024Observational
- Minimal Invasive Versus Open Surgery for Colorectal Liver Metastases: A Multicenter German StuDoQ|Liver Registry-Based Cohort Analysis in Germany.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2023Article
- Psychiatric disorder and its association with gastrointestinal cancer: a retrospective cohort study with 45,842 patients in Germany.Journal of cancer research and clinical oncology · 2023Article
- Evaluation of Colonoscopic Results of Patients with Incidental Colonic FDG Uptake in PET/CT Imaging.World journal of surgery · 2023Article
- Beneficial effects of alpha-1 antitrypsin therapy in a mouse model of colitis-associated colon cancer.BMC cancer · 2023Article
- Characteristics of familial pancreatic cancer families with additional colorectal carcinoma.Familial cancer · 2023Article
- [Metastatic colorectal cancer-Modern treatment strategies and sequences].Innere Medizin (Heidelberg, Germany) · 2023Article
- International study on the prevalence of malnutrition in centralized care for colorectal cancer patients.Innovative surgical sciences · 2023Article
- The Epidemiology of Colorectal Cancer in Younger and Older Patients.Deutsches Arzteblatt international · 2023Article
- [What is confirmed in the treatment of colon cancer?]Innere Medizin (Heidelberg, Germany) · 2022Review
- 10-year prevalence of diagnostic and screening colonoscopy use in Germany: a claims data analysis.European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) · 2022Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe use of colonoscopy has increased and colorectal cancer (CRC) incidence has decreased after the introduction of screening colonoscopy in Germany. However, it remains unknown to what extent progress has been achieved in the prevention of cancer in the proximal colon, distal colon, and rectum.
methodsWe analyzed trends in CRC incidence (2000-2016) and mortality (2000-2018) in Germany by sex, age, and tumor location.
resultsThe age-standardized incidence of CRC declined by 22.4% (from 65.3 to 50.7 per 100 000) in men and by 25.5% (from 42.7 to 31.8 per 100 000) in women. CRC mortality declined by 35.8% (from 29.6 to 19.0 per 100 000) in men and by 40.5% (19.0 to 11.3 per 100 000) in women. Despite demographic changes, the annual numbers of CRC cases and deaths still decreased from about 60 400 to 58 300 and from around 28 700 to 24 200, respectively. The decline in incidence was greatest in groups aged ≥ 55 years. While the incidence of cancer in the distal colon and rectum decreased by 34.5% and 26.2%, respectively, in men and by 41.0% and 27.9% in women, the incidence of proximal colon cancer remained stable in men and decreased by only 7.0% in women. However, a major shift towards earlier stages was observed for the proximal cancers.
conclusionThe results support the assumption that the increased use of colo - noscopy has contributed to substantial reductions in the incidence of distal CRC incidence and the mortality from cancers in the entire colon and rectum.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.