Evidence map›Paper›PMID 34180721›Full record

ArticleAIDS care2022

Cannabis use, pain interference, and prescription opioid receipt among persons with HIV: a target trial emulation study.

William C Becker, Yu Li, Ellen C Caniglia, Rachel Vickers-Smith, Termeh Feinberg, Brandon D L Marshall, E Jennifer Edelman

Open access · greenAbstract read
In one paragraph

Article in AIDS care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

William C BeckerVA Connecticut Healthcare System, West Haven, CT, USA.ORCID 0000-0002-0788-1467
Yu LiDepartment of Epidemiology, Brown University School of Public Health, Providence, RI, USA.
Ellen C CanigliaDepartment of Population Health, NYU Grossman School of Medicine, New York, USA.
Rachel Vickers-SmithDepartment of Epidemiology, University of Kentucky College of Public Health, Lexington, KY, USA.
Termeh FeinbergVA Connecticut Healthcare System, West Haven, CT, USA.
Brandon D L MarshallDepartment of Epidemiology, Brown University School of Public Health, Providence, RI, USA.ORCID 0000-0002-0134-7052
E Jennifer EdelmanYale School of Medicine, New Haven, CT, USA.
Yale University · USBrown University · USNew York University · USUniversity of Kentucky · US

Funding

Alcohol and Multisubstance Use in the Veterans Aging Cohort StudyU01AA020790 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2011 to 2020
$7.7M
Non-Medical Use of Prescription Opioids Among HIV-Infected Individuals: Trajectories and Impact on Health OutcomesR01DA040471 · NIDA · YALE UNIVERSITY · PI EDELMAN, E. JENNIFER · 2016 to 2018
$716k
NIAAA NIH HHS U01 AA020790NIDA NIH HHS R01 DA040471
6 · The paper itself

Abstract

Concomitant with expanded legalization, cannabis is increasingly used to treat chronic pain among persons with HIV (PWH), despite equivocal benefit in research limited by small sample sizes and short duration of follow-up. To address these limitations, among a sample of PWH with pain interference enrolled in the Veterans Aging Cohort Study, we performed a target trial emulation study to compare the impact of four cannabis use strategies on pain interference. Among those receiving long-term opioid therapy (LTOT), we also explored impact of these strategies on ≥ 25% LTOT dose reduction. Among the analytic sample (

Indexed as

CannabisChronic PainHIV InfectionsAnalgesics, OpioidCohort StudiesFemaleHumansMaleMiddle AgedPrescriptionsAnalgesics, Opioidcannabis useChronic painlong-term opioid therapytarget trial emulation study

Identifiers

PMID34180721
PMCPMC10450359
OpenAlexW3174638597

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.