Evidence map›Paper›PMID 34180599›Full record

ArticleMicrobiologyOpen2021

Low-carbohydrate high-fat weight reduction diet induces changes in human gut microbiota.

Madis Jaagura, Ene Viiard, Kätrin Karu-Lavits, Kaarel Adamberg

Open access · goldAbstract read
In one paragraph

Article in MicrobiologyOpen, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Madis JaaguraCenter of Food and Fermentation Technologies, Tallinn, 12618, Estonia.ORCID 0000-0003-2329-0242
Ene ViiardCenter of Food and Fermentation Technologies, Tallinn, 12618, Estonia.
Kätrin Karu-LavitsCenter of Food and Fermentation Technologies, Tallinn, 12618, Estonia.
Kaarel AdambergCenter of Food and Fermentation Technologies, Tallinn, 12618, Estonia.
Tallinn University of Technology · EE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity has become a major public health problem in recent decades. More effective interventions may result from a better understanding of microbiota alterations caused by weight loss and diet. Our objectives were (a) to calculate the fiber composition of a specially designed low-calorie weight loss diet (WLD), and (b) to evaluate changes in the composition of gut microbiota and improvements in health characteristics during WLD. A total of 19 overweight/obese participants were assigned to 20%-40% reduced calories low-carbohydrate high-fat diet for four weeks. Protein and fat content in the composed diet was 1.5 times higher compared to that in the average diet of the normal weight reference group, while carbohydrate content was 2 times lower. Food consumption data were obtained from the assigned meals. Microbial composition was analyzed before and after WLD intervention from two sequential samples by 16S rRNA gene sequencing. During WLD, body mass index (BMI) was reduced on average 2.5 ± 0.6 kg/m

Indexed as

Gastrointestinal MicrobiomeAdultBacteriaBody Mass IndexDiet, Carbohydrate-RestrictedDiet, High-FatDNA, BacterialFecesFemaleHumansMaleObesityOverweightPhylogenyRNA, Ribosomal, 16SWeight LossDNA, BacterialRNA, Ribosomal, 16S16S rRNA genebifidobacteriaBMICollinsellamicrobiomeobesityweight loss

Identifiers

PMID34180599
PMCPMC8123914
OpenAlexW3163838745

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.