Evidence map›Paper›PMID 34180581›Full record

Observational studyActa ophthalmologica2022

Prevalence and incidence of diabetic retinopathy (DR) in the UK population of Gloucestershire.

Peter H Scanlon, Clareece R Nevill, Irene M Stratton, Sonia S Maruti, Elvira L Massó-González, Sobha Sivaprasad, Clare Bailey, Michael Ehrlich, Victor Chong

Abstract readObservational Study
In one paragraph

Observational study in Acta ophthalmologica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Retinopathy prevalence, incidence and trajectories in type 2 diabetes: The Fremantle diabetes study phase II.Diabetic medicine : a journal of the British Diabetic Association · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Peter H ScanlonGloucestershire Retinal Research Group, Cheltenham General Hospital, Cheltenham, UK.ORCID https://orcid.org/0000-0001-8513-710X
Clareece R NevillGloucestershire Retinal Research Group, Cheltenham General Hospital, Cheltenham, UK.
Irene M StrattonGloucestershire Retinal Research Group, Cheltenham General Hospital, Cheltenham, UK.
Sonia S MarutiBoehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT, USA.
Elvira L Massó-GonzálezBoehringer Ingelheim International GmBH, Ingelheim, Germany.
Sobha SivaprasadMoorfields Eye Hospital, London, UK.ORCID https://orcid.org/0000-0001-8952-0659
Clare BaileyBristol Eye Hospital, Bristol, UK.
Michael EhrlichBoehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT, USA.
Victor ChongBoehringer Ingelheim International GmBH, Ingelheim, Germany.

Funding

Boehringer Ingelheim International GmBH
6 · The paper itself

Abstract

purposeTo estimate prevalence and incidence of diabetic retinopathy (DR) in a UK region by severity between 2012 and 2016 and risk factors for progression to proliferative DR (PDR).

methodsElectronic medical records from people with diabetes (PWD) ≥18 years seen at the Gloucestershire Diabetic Eye Screening Programme (GDESP) and the hospital eye clinic were analysed (HEC). Prevalence and incidence of DR per 100 PWD (%) by calendar year, grade and diabetes type were estimated using log-linear regression. Progression to PDR and associated risk factors were estimated using parametric survival analyses.

resultsAcross the study period, 35 873 PWD had at least one DR assessment. They were aged 66 (56-75) years (median (interquartile range)), 57% male, 5 (1-10) years since diabetes diagnosis, 93% Type 2 diabetes. Prevalence of DR decreased from 38.9% (95% CI: 38.1%, 39.8%) in 2012 to 36.6% (95% CI: 35.9%, 37.3%) in 2016 (p < 0.001). Incidence of any DR decreased from 10.9% (95% CI: 10.4%, 11.5%) in 2013 to 8.5% (95% CI: 8.1%, 9.0%) in 2016 (p < 0.001). Prevalence of PDR decreased from 3.5% (95% CI: 3.3%, 3.8%) in 2012 to 3.1% (95% CI 2.9%, 3.3%) in 2016 (p = 0.008). Incidence of PDR did not change over time. HbA

conclusionsIncidence and prevalence of DR decreased between 2012 and 2016 in this well-characterized population of the UK.

Indexed as

AgedDiabetic RetinopathyDisease ProgressionEnglandFemaleHumansIncidenceMaleMass ScreeningMiddle AgedPrevalenceRetrospective StudiesRisk Factorsdiabetic retinopathyepidemiologyimagingretinal screeningsight-threatening diabetic retinopathy

Identifiers

PMID34180581
PMCPMC9290830

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.