Evidence map›Paper›PMID 34180396›Full record

ArticleeLife2021

A novel decoy strategy for polymyxin resistance in

Jaeeun Park, Misung Kim, Bora Shin, Mingyeong Kang, Jihye Yang, Tae Kwon Lee, Woojun Park

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.

  1. Pooled it
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  6. Review
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  8. Bacteriophages targetingFrontiers in microbiology · 2026
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  9. Sphingolipid-mediated vesiculation in multidrug-resistantApplied and environmental microbiology · 2025
    Article
  10. Article
  11. Article
  12. Review
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  17. Article
  18. Review
  19. Article
  20. Roles of DJ41_1407 and DJ41_1408 inInternational journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jaeeun Park *Laboratory of Molecular Environmental Microbiology, Department of Environmental Science and Ecological Engineering, Korea University, Seoul, Republic of Korea.
Misung Kim *Laboratory of Molecular Environmental Microbiology, Department of Environmental Science and Ecological Engineering, Korea University, Seoul, Republic of Korea.
Bora Shin *Laboratory of Molecular Environmental Microbiology, Department of Environmental Science and Ecological Engineering, Korea University, Seoul, Republic of Korea.
Mingyeong KangLaboratory of Molecular Environmental Microbiology, Department of Environmental Science and Ecological Engineering, Korea University, Seoul, Republic of Korea.
Jihye YangLaboratory of Molecular Environmental Microbiology, Department of Environmental Science and Ecological Engineering, Korea University, Seoul, Republic of Korea.
Tae Kwon LeeDepartment of Environmental Engineering, Yonsei University, Wonju, Republic of Korea.ORCID 0000-0003-3845-7316
Woojun ParkLaboratory of Molecular Environmental Microbiology, Department of Environmental Science and Ecological Engineering, Korea University, Seoul, Republic of Korea.ORCID 0000-0002-3166-1528
Korea University · KRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modification of the outer membrane charge by a polymyxin B (PMB)-induced PmrAB two-component system appears to be a dominant phenomenon in PMB-resistant

Indexed as

Acinetobacter baumanniiAdultAnimalsAnti-Bacterial AgentsBiofilmsDrug Resistance, BacterialEscherichia coliFecesFemaleHumansLarvaLipid AMicroscopy, Electron, TransmissionMothsPolymyxin BSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationAnti-Bacterial AgentsLipid APolymyxin Bacinetobacter baumanniicomponent regulatory systemsexperimental evolutioninfectious diseaselps modificationsmicrobiologyouter membrane vesiclpolymyxin resistance

Identifiers

PMID34180396
PMCPMC8324293
OpenAlexW3173380115

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.