Evidence map›Paper›PMID 34180355›Full record

ArticleCell cycle (Georgetown, Tex.)2021

A nuclear proteome localization screen reveals the exquisite specificity of Gpn2 in RNA polymerase biogenesis.

Sean W Minaker, Megan C Kofoed, Philip Hieter, Peter C Stirling

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sean W MinakerTerry Fox Laboratories, BC Cancer Research Institute, Vancouver, Canada.
Megan C KofoedMichael Smith Laboratory, University of British Columbia, Vancouver, Canada.
Philip HieterMichael Smith Laboratory, University of British Columbia, Vancouver, Canada.
Peter C StirlingTerry Fox Laboratories, BC Cancer Research Institute, Vancouver, Canada.
Canada's Michael Smith Genome Sciences Centre · CATerry Fox Research Institute · CA

Funding

CIHR
6 · The paper itself

Abstract

The GPN proteins are a conserved family of GTP-binding proteins that are involved in the assembly and subsequent import of RNA polymerase II and III. In this study, we sought to ascertain the specificity of yeast GPN2 for RNA polymerases by screening the localization of a collection of 1350 GFP-tagged nuclear proteins in WT or

Indexed as

Monomeric GTP-Binding ProteinsSaccharomyces cerevisiae ProteinsDNA-Directed RNA PolymerasesPhosphorylationProteomeRNA Polymerase IISaccharomyces cerevisiaeDNA-Directed RNA PolymerasesGPN2 protein, S cerevisiaeMonomeric GTP-Binding ProteinsProteomeRNA Polymerase IISaccharomyces cerevisiae Proteinsfunctional genomicsGPN2protein complex biogenesisRNA polymeraseyeast

Identifiers

PMID34180355
PMCPMC8344759
OpenAlexW3174997895

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.