Evidence map›Paper›PMID 34180223›Full record

ArticleACS applied materials & interfaces2021

Zinc-Embedded Polyamide Fabrics Inactivate SARS-CoV-2 and Influenza A Virus.

Vikram Gopal, Benjamin E Nilsson-Payant, Hollie French, Jurre Y Siegers, Wai-Shing Yung, Matthew Hardwick, Aartjan J W Te Velthuis

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Disinfection methods against SARS-CoV-2: a systematic review.The Journal of hospital infection · 2022
    Pooled it
  2. In Vitro Assessment ofGlobal challenges (Hoboken, NJ) · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. SyntheticRSC advances · 2024
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. A Novel Antipathogenic Agent for Nonwoven Fabric.Biomedical materials & devices (New York, N.Y.) · 2022
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Vikram GopalAscend Performance Materials, 1010 Travis Street, Suite 900, Houston, Texas 77002, United States.
Benjamin E Nilsson-PayantDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.
Hollie FrenchDivision of Virology, Department of Pathology, Addenbrooke's Hospital, University of Cambridge, Hills Road, Cambridge CB2 2QQ, U.K.
Jurre Y SiegersDepartment of Viroscience, Erasmus University Medical Centre, Rotterdam 3015 GD, the Netherlands.
Wai-Shing YungAscend Performance Materials, 1010 Travis Street, Suite 900, Houston, Texas 77002, United States.
Matthew HardwickResInnova Laboratories, 8807 Colesville Rd, 3rd Floor, Silver Spring, Maryland 20910, United States.
Aartjan J W Te VelthuisDivision of Virology, Department of Pathology, Addenbrooke's Hospital, University of Cambridge, Hills Road, Cambridge CB2 2QQ, U.K.ORCID https://orcid.org/0000-0002-5129-3953

Funding

Wellcome Trust 206579/Z/17/Z
6 · The paper itself

Abstract

Influenza A viruses (IAV) and SARS-CoV-2 can spread via liquid droplets and aerosols. Face masks and other personal protective equipment (PPE) can act as barriers that prevent the spread of these viruses. However, IAV and SARS-CoV-2 are stable for hours on various materials, which makes frequent and correct disposal of these PPE important. Metal ions embedded into PPE may inactivate respiratory viruses, but confounding factors such as adsorption of viruses make measuring and optimizing the inactivation characteristics difficult. Here, we used polyamide 6.6 (PA66) fibers containing embedded zinc ions and systematically investigated if these fibers can adsorb and inactivate SARS-CoV-2 and IAV H1N1 when woven into a fabric. We found that our PA66-based fabric decreased the IAV H1N1 and SARS-CoV-2 titer by approximately 100-fold. Moreover, we found that the zinc content and the virus inactivating property of the fabric remained stable over 50 standardized washes. Overall, these results provide insights into the development of reusable PPE that offer protection against RNA virus spread.

Indexed as

TextilesAdsorptionAnimalsChlorocebus aethiopsCotton FiberDogsHEK293 CellsHumansInfluenza A virusIonsMadin Darby Canine Kidney CellsNylonsPolypropylenesSARS-CoV-2Vero CellsViral LoadIonsNylonsPolypropylenesZincZinc Oxideabsorptioncoronavirusface maskinfluenzazinc

Identifiers

PMID34180223
PMCPMC8262172

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.