Evidence map›Paper›PMID 34179503›Full record

ArticleOpen medicine (Warsaw, Poland)2021

Significance of miR-141 and miR-340 in cervical squamous cell carcinoma.

Wenting Li, Bo Yang, Yiqun Li, Cuicui Wang, Xinzhi Fang

Abstract read
In one paragraph

Article in Open medicine (Warsaw, Poland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wenting LiDepartment of Pathology, Shenzhen University General Hospital, No. 1098 Xueyuan Road, Nanshan District, Shenzhen 518055, China.
Bo YangDepartment of Pathology, Affiliated Tumor Hospital of Xinjiang Medical University, Urumqi 830011, Xinjiang, China.
Yiqun LiDepartment of Pathology, Affiliated Tumor Hospital of Xinjiang Medical University, Urumqi 830011, Xinjiang, China.
Cuicui WangDepartment of Pathology, Affiliated Tumor Hospital of Xinjiang Medical University, Urumqi 830011, Xinjiang, China.
Xinzhi FangDepartment of Pathology, Affiliated Tumor Hospital of Xinjiang Medical University, Urumqi 830011, Xinjiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe investigated the expression and clinical significance of miR-141 and miR-340 in cervical squamous cell carcinoma (CSCC).

methodsExpression of miR-141 and miR-340 in CSCC, high-grade squamous intraepithelial lesion (HSIL), and normal cervical squamous epithelium were detected by qRT-PCR. PTEN was assessed by immunohistochemistry. Their relationship with clinicopathological features was analyzed.

resultsThe changes of miR-141 and miR-340 were different in CSCC, HSIL, and normal squamous epithelium (

conclusionmiR-141 and miR-340 may be associated with their target gene PTEN and involved in the carcinogenesis of cervical squamous epithelium.

Indexed as

cervical squamous cell carcinomahigh-grade squamous intraepithelial lesionmiR-141miR-340PTEN

Identifiers

PMID34179503
PMCPMC8209411

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.