Evidence map›Paper›PMID 34179172›Full record

ArticleFrontiers in veterinary science2021

Evaluation of Three Commercial Interferon-γ Assays in a Bovine Tuberculosis Free Population.

Giovanni Ghielmetti, Patricia Landolt, Ute Friedel, Marina Morach, Sonja Hartnack, Roger Stephan, Sarah Schmitt

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Bovine tuberculosis reactor cattle in Southwest Ethiopia: Risk factors for bovine tuberculosis.Journal of clinical tuberculosis and other mycobacterial diseases · 2024
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Vaccination of Calves with theAnimals : an open access journal from MDPI · 2022
    Article
  8. Infection of a Free-Living Wild Boar (Animals : an open access journal from MDPI · 2022
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Giovanni GhielmettiSection of Veterinary Bacteriology, Institute for Food Safety and Hygiene, University of Zurich, Zurich, Switzerland.
Patricia LandoltSection of Veterinary Bacteriology, Institute for Food Safety and Hygiene, University of Zurich, Zurich, Switzerland.
Ute FriedelSection of Veterinary Bacteriology, Institute for Food Safety and Hygiene, University of Zurich, Zurich, Switzerland.
Marina MorachInstitute for Food Safety and Hygiene, University of Zurich, Zurich, Switzerland.
Sonja HartnackSection of Epidemiology, University of Zurich, Zurich, Switzerland.
Roger StephanSection of Veterinary Bacteriology, Institute for Food Safety and Hygiene, University of Zurich, Zurich, Switzerland.
Sarah SchmittSection of Veterinary Bacteriology, Institute for Food Safety and Hygiene, University of Zurich, Zurich, Switzerland.
University of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The interferon-γ assay has been used worldwide as an ancillary test for the diagnosis of bovine tuberculosis (bTB). This study aimed to describe, based on the bTB-free status in Switzerland, the difference of applying a more stringent cutoff point of 0.05 compared with 0.1 for bTB surveillance. Moreover, the effect of time between blood collection and stimulation, culture results, optical density values, and the influence of testing different breeds were evaluated. Blood samples from a total of 118 healthy cows older than 6 months were tested with three commercial interferon-gamma assays. To confirm the bTB-free status of the tested animals and to investigate potential cross-reactions with nontuberculous mycobacteria, pulmonary and abdominal lymph nodes in addition to ileal mucosa from each cattle were used for the detection of viable

Indexed as

bovine tuberculosiscattlediagnosisinterferon-gamma assayMycobacterium avium subsp hominissuisMycobacterium avium subsp paratuberculosisMycobacterium bovisMycobacterium persicum

Identifiers

PMID34179172
PMCPMC8222658
OpenAlexW3167499995

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.