Evidence map›Paper›PMID 34179081›Full record

ArticleFrontiers in molecular biosciences2021

MicroRNAs Regulating Tumor Immune Response in the Prediction of the Outcome in Patients With Breast Cancer.

Konstantina Thomopoulou, Chara Papadaki, Alexia Monastirioti, George Koronakis, Anastasia Mala, Despoina Kalapanida, Dimitrios Mavroudis, Sofia Agelaki

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Konstantina ThomopoulouDepartment of Medical Oncology, University General Hospital, Crete, Heraklion, Greece.
Chara PapadakiLaboratory of Translational Oncology, School of Medicine, University of Crete, Heraklion, Greece.
Alexia MonastiriotiLaboratory of Translational Oncology, School of Medicine, University of Crete, Heraklion, Greece.
George KoronakisDepartment of Medical Oncology, University General Hospital, Crete, Heraklion, Greece.
Anastasia MalaDepartment of Medical Oncology, University General Hospital, Crete, Heraklion, Greece.
Despoina KalapanidaDepartment of Medical Oncology, University General Hospital, Crete, Heraklion, Greece.
Dimitrios MavroudisDepartment of Medical Oncology, University General Hospital, Crete, Heraklion, Greece.
Sofia AgelakiDepartment of Medical Oncology, University General Hospital, Crete, Heraklion, Greece.
University of Crete · GRUniversity Hospital of Heraklion · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) are key regulators in immune surveillance and immune escape as well as modulators in the metastatic process of breast cancer cells. We evaluated the differential expression of plasma miR-10b, miR-19a, miR-20a, miR-126 and miR-155, which regulate immune response in breast cancer progression and we investigated their clinical relevance in the outcomes of breast cancer patients. Plasma samples were obtained from early (eBC;

Indexed as

circulating miRNAsearly breast cancerimmune responsemetastatic breast cancerprognosis

Identifiers

PMID34179081
PMCPMC8220200
OpenAlexW3170822167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.