Evidence map›Paper›PMID 34179040›Full record

ArticleFrontiers in medicine2021

Blood Eosinophils and Clinical Outcomes in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Propensity Score Matching Analysis of Real-World Data in China.

Yanan Cui, Zijie Zhan, Zihang Zeng, Ke Huang, Chen Liang, Xihua Mao, Yaowen Zhang, Xiaoxia Ren, Ting Yang, Yan Chen

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05059873 (A Multicenter Double-blind Randomized Controlled Trial of Systemic Corticosteroid Therapy in AECOPD Patients Admitted to Hospital With Higher Blood Eosinophil Levels), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05059873 phase4terminatednot on this mapstarted 2023, after this paper: background citation

A Multicenter Double-blind Randomized Controlled Trial of Systemic Corticosteroid Therapy in AECOPD Patients Admitted to Hospital With Higher Blood Eosinophil Levels

TypeinterventionalSponsorCapital Medical UniversityRan2023 to 2024Enrolled11ConditionsAcute Exacerbation of COPD, Corticosteroid, Morality, Lung Diseases, ObstructiveArmsPrednisone, Placebo
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Eosinophil count and treatment response in COPD patients.Lung India : official organ of Indian Chest Society · 2025
    Article
  4. Review
  5. Article
  6. Clinical Characteristics and Outcomes of Eosinophilic Exacerbations of COPD.International journal of chronic obstructive pulmonary disease · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Observational
  12. Article
  13. Article
  14. Article
  15. Article
  16. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Yanan CuiDepartment of Respiratory and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Changsha, China.
Zijie ZhanDepartment of Respiratory and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Changsha, China.
Zihang ZengDepartment of Respiratory and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Changsha, China.
Ke HuangDepartment of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, China.
Chen LiangChinese Alliance for Respiratory Diseases in Primary Care, Beijing, China.
Xihua MaoChinese Alliance for Respiratory Diseases in Primary Care, Beijing, China.
Yaowen ZhangChinese Alliance for Respiratory Diseases in Primary Care, Beijing, China.
Xiaoxia RenDepartment of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, China.
Ting YangDepartment of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, China.
Yan ChenDepartment of Respiratory and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Changsha, China.
China-Japan Friendship Hospital · CNSecond Xiangya Hospital of Central South University · CNCentral South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AECOPDcorticosteroidseosinophilspredictionsmoking

Identifiers

PMID34179040
PMCPMC8219875
OpenAlexW3170286820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.