Evidence map›Paper›PMID 34178967›Full record

ReviewFrontiers in bioengineering and biotechnology2021

The Rheology of the Carotid Sinus: A Path Toward Bioinspired Intervention.

Andrew Iskander, Coskun Bilgi, Rotem Naftalovich, Ilker Hacihaliloglu, Tolga Berkman, Daniel Naftalovich, Niema Pahlevan

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. On the Longitudinal Wave Pumping in Fluid-filled Compliant Tubes.Physics of fluids (Woodbury, N.Y. : 1994) · 2023
    Article
  3. Article
  4. Clarification on viscosity vs. viscoelasticity.Anaesthesiology intensive therapy · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Andrew IskanderDepartment of Anesthesiology, Westchester Medical Center, New York Medical College, Valhalla, NY, United States.
Coskun BilgiDepartment of Aerospace and Mechanical Engineering, University of Southern California, Los Angeles, CA, United States.
Rotem NaftalovichDepartment of Anesthesiology, New Jersey Medical School, University Hospital, Rutgers University, Newark, NJ, United States.
Ilker HacihalilogluDepartment of Biomedical Engineering, Rutgers School of Engineering, Rutgers University, Piscataway, NJ, United States.
Tolga BerkmanDepartment of Anesthesiology, New Jersey Medical School, University Hospital, Rutgers University, Newark, NJ, United States.
Daniel NaftalovichDepartment of Computational and Mathematical Sciences, California Institute of Technology, Pasadena, CA, United States.
Niema PahlevanDepartment of Aerospace and Mechanical Engineering, University of Southern California, Los Angeles, CA, United States.
Rutgers, The State University of New Jersey · USUniversity of Southern California · USCalifornia Institute of Technology · USUnited States Army Medical Command · USWestchester Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The association between blood viscosity and pathological conditions involving a number of organ systems is well known. However, how the body measures and maintains appropriate blood viscosity is not well-described. The literature endorsing the function of the carotid sinus as a site of baroreception can be traced back to some of the earliest descriptions of digital pressure on the neck producing a drop in blood delivery to the brain. For the last 30 years, improved computational fluid dynamic (CFD) simulations of blood flow within the carotid sinus have demonstrated a more nuanced understanding of the changes in the region as it relates to changes in conventional metrics of cardiovascular function, including blood pressure. We suggest that the unique flow patterns within the carotid sinus may make it an ideal site to transduce flow data that can, in turn, enable real-time measurement of blood

Indexed as

baroreceptorblood flowcarotid sinusPIEZO receptorviscosity

Identifiers

PMID34178967
PMCPMC8222608
OpenAlexW3172485619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.