Evidence map›Paper›PMID 34178920›Full record

SynthesisFrontiers in public health2021

Reinfection or Reactivation of Severe Acute Respiratory Syndrome Coronavirus 2: A Systematic Review.

Xiujuan Tang, Salihu S Musa, Shi Zhao, Daihai He

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Epidemiological assessment of SARS-CoV-2 reinfection.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
    Article
  5. Review
  6. Article
  7. SARS-CoV-2 symptomatic reinfection among patients with primary antibody deficiency.The journal of allergy and clinical immunology. In practice · 2022
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Suspected reinfections of SARS-COV-The Journal of infection · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Reinfection by SARS CoV2 in Valle Del Cauca, Colombia: A Descriptive Retrospective Study.Inquiry : a journal of medical care organization, provision and financing
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Xiujuan TangShenzhen Center for Disease Control and Prevention, Shenzhen, China.
Salihu S MusaDepartment of Applied Mathematics, The Hong Kong Polytechnic University, Hong Kong, China.
Shi ZhaoJockey Club School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong, China.
Daihai HeDepartment of Applied Mathematics, The Hong Kong Polytechnic University, Hong Kong, China.
Hong Kong Polytechnic University · HKHong Kong Jockey Club · CNShenzhen Center for Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the pandemic continues, individuals with re-detectable positive (RP) SARS-CoV-2 viral RNA among recovered COVID-19 patients have raised public health concerns. It is imperative to investigate whether the cases with re-detectable positive (RP) SARS-CoV-2 might cause severe infection to the vulnerable population. In this work, we conducted a systematic review of recent literature to investigate reactivation and reinfection among the discharged COVID-19 patients that are found positive again. Our study, consisting more than a total of 113,715 patients, indicates that the RP-SARS-CoV-2 scenario occurs plausibly due to reactivation, reinfection, viral shedding, or testing errors. Nonetheless, we observe that previously infected individuals have significantly lower risk of being infected for the second time, indicating that reactivation or reinfection of SARS-CoV-2 likely have relatively less impact in the general population than the primary infection.

Indexed as

COVID-19SARS-CoV-2HumansPandemicsReinfectionVirus SheddingCOVID-19pandemicreactivationre-detectable positivereinfection

Identifiers

PMID34178920
PMCPMC8226004
OpenAlexW3166179283

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.