Evidence map›Paper›PMID 34178715›Full record

ArticleFrontiers in cellular and infection microbiology2021

Polyphenol Enriched Diet Administration During Pregnancy and Lactation Prevents Dysbiosis in Ulcerative Colitis Predisposed Littermates.

Stefania De Santis, Aurelia Scarano, Marina Liso, Francesco Maria Calabrese, Giulio Verna, Elisabetta Cavalcanti, Annamaria Sila, Antonio Lippolis, Maria De Angelis, Angelo Santino and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Early life factors, diet and microbiome, and risk of inflammatory bowel disease.Journal of the Canadian Association of Gastroenterology · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Stefania De SantisDepartment of Pharmacy-Drug Science, University of Bari Aldo Moro, Bari, Italy.
Aurelia ScaranoInstitute of Sciences of Food Production National Research Council (CNR), Unit of Lecce, Lecce, Italy.
Marina LisoNational Institute of Gastroenterology "S. de Bellis", Research Hospital, Castellana Grotte, Italy.
Francesco Maria CalabreseDepartment of Soil, Plant and Food Sciences, University of Bari, Bari, Italy.
Giulio VernaDepartment of Pharmacy, University of Salerno, Fisciano, Italy.
Elisabetta CavalcantiNational Institute of Gastroenterology "S. de Bellis", Research Hospital, Castellana Grotte, Italy.
Annamaria SilaNational Institute of Gastroenterology "S. de Bellis", Research Hospital, Castellana Grotte, Italy.
Antonio LippolisNational Institute of Gastroenterology "S. de Bellis", Research Hospital, Castellana Grotte, Italy.
Maria De AngelisDepartment of Soil, Plant and Food Sciences, University of Bari, Bari, Italy.
Angelo SantinoInstitute of Sciences of Food Production National Research Council (CNR), Unit of Lecce, Lecce, Italy.
Marcello ChieppaNational Institute of Gastroenterology "S. de Bellis", Research Hospital, Castellana Grotte, Italy.
Gastroenterology Hospital "Saverio de Bellis" · ITUniversity of Bari Aldo Moro · ITInstitute of Sciences of Food Production · ITUniversity of Salerno · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neonatal colonization of the gastrointestinal tract depends on mother microbiome, thus mother microbiota dysbiosis is transmitted to the offspring during the delivery and shaped by breastmilk characteristics. Here we used a murine model of UC predisposition (Winnie

Indexed as

Colitis, UlcerativeGastrointestinal MicrobiomeAnimalsDietDisease Models, AnimalDysbiosisFemaleLactationMiceMice, Inbred C57BLPolyphenolsPregnancyPolyphenolsanimal modelmicrobiotanutritionpolyphenolsulcerative colitis

Identifiers

PMID34178715
PMCPMC8221423
OpenAlexW3167183258

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.