Evidence map›Paper›PMID 34178654›Full record

ArticleFrontiers in oncology2021

A Pilot Study of Home-Based Exercise and Personalized Nutrition Counseling Intervention in Endometrial Cancer Survivors.

Amanda R Schwartz, David B Bartlett, Johanna L Johnson, Gloria Broadwater, Meghan Channell, Kimberly C Nolte, Patricia A Wilkes, Kim M Huffman, Angeles Alvarez Secord

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02987881 (Physical Activity and Nutrition Counseling Intervention in Endometrial Cancer Survivors), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02987881 nacompletednot on this map

Physical Activity and Nutrition Counseling Intervention in Endometrial Cancer Survivors

TypeinterventionalSponsorDuke UniversityRan2017 to 2019Enrolled16ConditionsEarly Stage Endometrial CancerArmsHome-based aerobic exercise and nutritional counseling
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Amanda R SchwartzDepartment of Obstetrics and Gynecology, Duke University Hospital, Durham, NC, United States.
David B BartlettDepartment of Medicine, Division of Medical Oncology, Duke University Hospital, Durham, NC, United States.
Johanna L JohnsonDuke Molecular Physiology Institute, Duke Center for Living, Duke University, Durham, NC, United States.
Gloria BroadwaterDepartment of Biostatistics and Bioinformatics, Duke Cancer Institute, Duke University Medical Center, Durham, NC, United States.
Meghan ChannellDepartment of Clinical Research, Duke Cancer Institute, Duke University Medical Center, Durham, NC, United States.
Kimberly C NolteDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Duke Cancer Institute, Duke University Health System, Durham, NC, United States.
Patricia A WilkesDepartment of Nutrition Services, Duke University Hospital, Durham, NC, United States.
Kim M HuffmanDuke Molecular Physiology Institute, Duke Center for Living, Duke University, Durham, NC, United States.
Angeles Alvarez SecordDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Duke Cancer Institute, Duke University Health System, Durham, NC, United States.
Duke University Hospital · USDuke University · USDuke University Health System · USDuke Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTo assess the feasibility of a home-based aerobic exercise and nutrition counseling intervention and effect on cardiorespiratory fitness, cardiovascular disease risk profile, and immune response in obese endometrial cancer survivors.

methodsA longitudinal pilot study assessed a 12-week home-based aerobic exercise and nutrition counseling intervention in obese endometrial cancer survivors. The primary outcome was feasibility defined as 80% adherence to weekly walking sessions calculated among individuals that completed the intervention. Secondary outcomes comprised pre- and post-intervention differences in cardiorespiratory fitness, cardiovascular risk factors, and T-cell function. Descriptive statistics summarized data. Wilcoxon sign tests identified differences between and pre and post-intervention variables.

resultsNineteen women with stage 1 endometrial cancer consented; 9 withdrew and one was a screen failure. Median adherence to weekly walking sessions was 83.3%. Body composition was significantly altered with a reduction in median fat mass from 52.5 kg to 46.9 kg (p=0.04), and BMI from 37.5 kg/m2 to 36.2 kg/m2 (p = 0.004). There was no significant difference in cardiorespiratory fitness or cardiovascular parameters. The percentage of CD4 DISCUSSION: Our home-based exercise and nutrition counseling program was feasible based on 80% adherence to walking sessions and favored altered body composition. However, the discontinuation rate was high and further research is needed to overcome barriers to implementation. Improvement in cardiovascular parameters will most likely require longer and more intensive programs.

Indexed as

cardiovascular diseaseendometrial cancerexercise intervention studynutrition intervention programobesity

Identifiers

PMID34178654
PMCPMC8232933
OpenAlexW3173100866

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.