Evidence map›Paper›PMID 34178574›Full record

ArticleCurrent developmental disorders reports2021

Correlates and clinical implications of tic suppressibility.

Keisuke Ueda, Soyoung Kim, Deanna J Greene, Kevin J Black

Abstract read
In one paragraph

Article in Current developmental disorders reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Knowledge and Awareness of Tourette's Syndrome among Teachers in Eastern Region, Saudi Arabia.Tremor and other hyperkinetic movements (New York, N.Y.) · 2026
    Article
  8. Article
  9. Article
  10. Review
  11. Sex and gender in neurodevelopmental conditions.Nature reviews. Neurology · 2023
    Review
  12. Review
  13. Article
  14. A Comprehensive Review of Tic Disorders in Children.Journal of clinical medicine · 2021
    Review
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Keisuke UedaDepartment of Neurology, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0003-4087-6018
Soyoung KimDepartment of Psychiatry, Washington University School of Medicine, St Louis, MO, USA.
Deanna J GreeneDepartment of Cognitive Science, University of California San Diego, La Jolla, CA, USA.
Kevin J BlackDepartment of Neurology, Washington University School of Medicine, St. Louis, MO, USA.

Funding

The New Tics Study: A Novel Approach to Pathophysiology and Cause of Tic DisordersR01MH104030 · NIMH · WASHINGTON UNIVERSITY · PI BLACK, KEVIN J · 2017 to 2021
$3.3M
Longitudinal Study of Brain Imaging and Cognitive Markers of Tourette Syndrome in ChildrenR01MH118217 · NIMH · WASHINGTON UNIVERSITY · PI GREENE, DEANNA JACQUELYN · 2019 to 2025
$3.2M
NIMH NIH HHS R01 MH104030NIMH NIH HHS R01 MH118217
6 · The paper itself

Abstract

purpose of reviewTic disorders are common in the pediatric population and are differentiated from other movement disorders by tic suppressibility. Understanding the mechanism of tic suppression may provide new insights to the pathophysiology of tic disorders. This article highlights clinical phenomenology and neuronal correlates of tic suppressibility. RECENT

findingsRecent studies suggest that tic suppressibility exists in children shortly after onset of their tics. Moreover, those who are better able to suppress their tics have better tic outcomes. Interoceptive awareness and automatic action inhibition may be involved in tic suppression. SUMMARY: We illustrate a possible underlying mechanism of tic suppressibility and its clinical correlations and implications. New concepts such as interoceptive awareness and action inhibition may help explain tic disorders. Further study will be useful to fill remaining knowledge gaps.

Indexed as

Inhibitionprovisional tic disorderpsychological [MeSH]suppressiontic disorders [MeSH]Tourette syndrome [MeSH]

Identifiers

PMID34178574
PMCPMC8224814

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.