Evidence map›Paper›PMID 34178546›Full record

ArticleCureus2021

Characteristics and Outcomes of Left Ventricular-Assist Device-Associated Cerebrovascular Events in Setting of Infectious Intracranial Aneurysms.

Tanu Garg, Shyam Panchal, Tariq Nisar, David McCane, Jason Lee, Ken Chyuan Ling, Barry Trachtenberg, Arvind Bhimaraj, David Chiu, Rajan Gadhia

Open access · diamondAbstract read
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 63% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Tanu GargVascular Neurology, Houston Methodist Hospital, Houston, USA.
Shyam PanchalVascular Neurology, Houston Methodist The Woodlands, Houston Methodist Neurological Institute, Houston, USA.
Tariq NisarNeurology, Houston Methodist Hospital, Houston, USA.
David McCaneNeurology, Houston Methodist Hospital, Houston, USA.
Jason LeeNeurology, Houston Methodist Hospital, Houston, USA.
Ken Chyuan LingNeurology, Houston Methodist Hospital, Houston, USA.
Barry TrachtenbergCardiology, Houston Methodist Hospital, Houston, USA.
Arvind BhimarajDeBakey Cardiology Associates, Houston Methodist Hospital, Houston, USA.
David ChiuNeurology, Houston Methodist Hospital, Houston, USA.
Rajan GadhiaNeurology, Houston Methodist Hospital, Houston Methodist Neurological Institute, Houston, USA.
Houston Methodist · USMethodist Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThe study aims to identify the characteristics and neurological outcomes of the left ventricular-assist device (LVAD)-associated cerebrovascular events (CVE) and infections, particularly in the setting of infectious intracranial aneurysms (IIA).

methodsA single-center retrospective review of patients having undergone LVAD implantation between 2011 and 2017 was conducted using institutional registries and screened for CVE. Patients with CVE were assessed for concurrent bacteremia; neurovascular imaging was then used to isolate patients with IIA. A review of comorbidities, imaging characteristics, and management were performed to determine predictors of neurological outcomes, as defined by the 90-day modified Rankin scale (mRS) scores.

resultsOf the 383 HeartMate II LVAD implantations performed, 43 all-cause stroke events were identified across 35 (9%) patients. The majority of the events were hemorrhagic CVE (n=28) with 21 events complicated by bacteremia. Of patients with hemorrhagic CVE and bacteremia,

conclusionOur results indicate that

Indexed as

bacteremiainfectious intracranial aneurysmleft ventricular assist devicelvadoutcomesstroke

Identifiers

PMID34178546
PMCPMC8224535
OpenAlexW3164687033

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.